Biography:Muneeb A. Faiq

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Short description: Kashmiri-American Neuroscientist
Muneeb A. Faiq
Muneeb Faiq at the Capitol Hill.jpg
Faiq at the Capitol Hill in 2019

Muneeb Faiq (born Srinagar, Kashmir) is a Kashmiri-American neuroscientist.[1][2][3] working on vision restoration and behavior[4] and is known for his work in glaucoma and neurodegenerative diseases.[5][6][7][8] He propounded the brain diabetes theory of glaucoma.[9][10][11] Other researchers have found scientific evidence in support of his theory.[12][13] His research also identified the involvement of acetylcholine system in glaucomatous vision loss [14] Muneeb was named National Alliance for Eye and Vision Research, Emerging Vision Scientist-2019,[15][16] USA and was invited to Capitol Hill, Washington D.C. to share his work.[17] According to Expertscape, his expertise ranks in the Top 0.5 percent of 36,544 published authors worldwide on Glaucoma.[18]

Life and career

Muneeb was born in Srinagar, Kashmir where he did his schooling, college, and university. He pursued a junior research fellowship in regenerative medicine and stem cell biology at the Cardiothoracic and Vascular Surgery Center, All India Institute of Medical Sciences, New Delhi, and worked under the mentorship of Panangipalli Venugopal and Balram Bhargava. Following this, he joined a Ph.D. program at Dr. Rajendra Prasad Center for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi where he studied the molecular genetics of glaucoma. During his studies on congenital glaucoma, he created a working guide for glaucoma specialist for treating patients and counseling the caretakers.[19][20] In 2014, Muneeb proposed the brain diabetes hypothesis (alternatively called Diabetes type-4) [21][22][23][24][25] – a theory that that explains the cause of vision loss in glaucoma and the involvement of the brain in this disorder.[26] Faiq presented initial findings of this research in the Annual Meeting and Association of Vision and Ophthalmology Research 2019, in Vancouver Canada.[27]

Faiq was awarded the Best PhD Scholar Award at All India Institute of Medical Science, New Delhi.[28][29] He received this award from Nata Menabde, executive director of the World Health Organisation and is the only Kashmiri to receive this award.[30] Currently, Faiq is working closely with Joel Schuman [31][32] (one of the inventors of the OCT technology) and Bernhard Sabel [33] (Director of the Institute of Medical Psychology, Magdeburg, Germany). Faiq also served as a columnist for Daily News and Analysis [34][35] (DNA) for a short time. He is a regular contributor to Philosophical Investigations[36] and his paper titled “Why is there something rather than nothing” [37] appeared in The Philosopher. The British philosopher Martin Cohen in his book Paradigm Shift describes Muneeb as a contemporary scientist with interesting philosophical insights.[38][39]

Contributions to science

Brain diabetes hypothesis

Glaucoma is an etiologically elusive disorder, its molecular mechanisms are largely unknown. Muneeb's research implicates brain insulin resistance as one of the causative factors in glaucoma[40] and hence his group dubbed this condition diabetes type 4.[41][42][43] Muneeb identified central insulin resistance as a reason for glaucomatous vision loss mediated through rise in intraocular pressure, inflammation, and retinal ganglion cell apoptosis.[44] These findings indicate that glaucoma might also have causality based in the central nervous system [45][46] and may have neurodegenerative correlates, making glaucoma similar to other neurodegenerative diseases including Alzheimer's disease and Parkinson's disease.

Mesentery as a single entity

Faiq was part of the research group that established established that mesentery,[47][48] a part of the human gut, is a single entity.[49][50] He developed a novel method of human cadaveric dissection.[51][52]

Mechanism of Zika Virus mediated Microcephaly

In 2016, Muneeb led a research study discovering a novel mechanism of Zika virus mediated brain defects in neonates.[53][54][55][56] They identified the involvement of retinoic acid signaling in Zika virus mediated microcephaly.[57][58]

Mindfulness based treatment of vision loss

In collaboration with German psychologists, Muneeb led a study establishing the therapeutic effects of meditation-based stress reduction in prevention and treatment of glaucoma.[59][60][61] In their research, they found that intraocular pressure is reduced by meditation and that may reduce further damage to the optic nerve and help to preserve the remaining vision in patients. According to their research, the reduction in stress hormones and inflammation suggests an overall improvement in the patient's quality of life.[62][63][64][65][66] Meditation appears to produce these benefits by reducing the physiological responses to stress.

References

  1. ↑ "Muneeb Faiq ResearchGate Profile". https://www.researchgate.net/profile/Muneeb_Faiq. 
  2. ↑ "Dr. Muneeb Faiq academic contributions and profile details on Association of Research in Vision and Ophthalmology". https://arvoconnect.arvo.org/profile?UserKey=870bae46-39a4-46cb-9bf4-4ed860c325c1. 
  3. ↑ "Dr. Faiq Muneeb AIIMS, New Delhi/NYU, New York Google Scholar Citations and academic contributions". https://scholar.google.co.in/citations?user=2FF3ERUAAAAJ&hl=en. 
  4. ↑ "ResearchGate score and records for latest scientific research on vision and Ophthalmology". https://www.researchgate.net/profile/Muneeb_Faiq. 
  5. ↑ "Annual Congress of the World Glaucoma Association in Hong Kong, Muneeb Faiq Lecture about the Future of Neuroprotective Strategies in Glaucoma". https://www.pathlms.com/wga/events/373/video_presentations/12921. 
  6. ↑ Faiq, M. A. (2018). "In Search of A Grand Unifying Theory for Glaucoma". Oman Journal of Ophthalmology 11 (2): 101–102. doi:10.4103/ojo.OJO_92_2018. PMID 29930441. 
  7. ↑ "Google Scholar Citation, i10 index and H-index of Dr. Muneeb Ahmad Faiq". https://scholar.google.co.in/citations?user=2FF3ERUAAAAJ&hl=en. 
  8. ↑ "Pathbreaking Discovery in the Field of Glaucoma, Is glaucoma Diabetes of the Brain". https://www.birlaeye.org/newsletter/eye-and-you-issue3.pdf. 
  9. ↑ "Glaucoma, The dark Matter of VIsion". https://www.visionaware.org/blog/visionaware-blog/could-glaucoma-actually-be-diabetes-of-the-brain-a-new-hypothesis-says-maybe/12. 
  10. ↑ "Glaucoma can actually be the diabetes of the brain, say researchers". https://medicalxpress.com/news/2014-04-glaucoma-diabetes-brain.html. 
  11. ↑ Faiq, M. A.; Dada, R.; Saluja, D.; Dada, T. (2014). "Glaucoma Diabetes of the Brain, A radical hypothesis about its nature and pathogenesis Medical Hypothesis 2014 Faiq et al". Medical Hypotheses 82 (5): 535–46. doi:10.1016/j.mehy.2014.02.005. PMID 24582331. 
  12. ↑ Hou, H.; Shoji, T.; Zangwill, L. M.; Moghimi, S.; Saunders, L. J.; Hasenstab, K.; Ghahari, E.; Manalastas, P. I. et al. (2018). "Canadian researchers support the brain diabetes hypothesis of glaucoma through their research". American Journal of Ophthalmology 189: 1–9. doi:10.1016/j.ajo.2018.02.002. PMID 29447914. 
  13. ↑ "Insulin could restore eye sight in glaucoma patients". 27 June 2018. https://coolblindtech.com/breakthrough-study-shows-insulin-eye-drops-could-restore-sight-of-glaucoma-patients/. 
  14. ↑ Faiq, M. A.; Wollstein, G.; Schuman, J. S.; Chan, K. C. (2019). "Cholinergic nervous system and glaucoma: From basic science to clinical applications". Progress in Retinal and Eye Research 72: 100767. doi:10.1016/j.preteyeres.2019.06.003. PMID 31242454. 
  15. ↑ "Emerging Vision Scientist 2019". https://www.eyeresearch.org/events/EVS2019. 
  16. ↑ "AIIMS alumnus named Emerging Vision Scientist-2019". https://www.indiamedicaltimes.com/2019/09/25/aiims-alumnus-named-emerging-vision-scientist-2019-in-usa/. 
  17. ↑ "Emerging Vision Scientist USA-2019". https://www.indiamedicaltimes.com/2019/09/25/aiims-alumnus-named-emerging-vision-scientist-2019-in-usa/. 
  18. ↑ "The expertise of Muneeb A. Faiq ranks in the Top 0.5% of 36,544 published authors worldwide on Glaucoma". http://www.expertscape.com/au/glaucoma/Faiq,+Muneeb+A. 
  19. ↑ "The expertise of Muneeb Ahmad Faiq ranks in the Top 0.5% of 36,544 published authors worldwide on Glaucoma". http://www.expertscape.com/au/glaucoma/Faiq,+Muneeb+A. 
  20. ↑ Prakash, Gyan; Iwata, Takeshi (3 November 2018). Muneeb Faiq gave a summary of the genetic research in India and other South Asian countries, Advances in Vision Research Vol II by Takeshi Iwata and Gyan Prakash, Springer Publications 2019. ISBN 9789811308840. https://books.google.com/books?id=mQ92DwAAQBAJ&pg=PA5&lpg=PA5&dq=muneeb+faiq#v=onepage. 
  21. ↑ "Medical Hypotheses Brain Glaucoma Theory Vol 82, Issue 5 Year 2014". https://www.sciencedirect.com/science/article/pii/S0306987714000516. 
  22. ↑ Dada, T. (2017). "Glaucoma diabetes of the brain". Journal of Current Glaucoma Practice 11 (3): 77–79. doi:10.5005/jp-journals-10028-1228. PMID 29151680. 
  23. ↑ "Eye World News and Opinion, Is vision restoration after glaucoma possible?". https://www.eyeworld.org/vision-restoration-after-glaucoma-possible. 
  24. ↑ "Kashmir Life and scientific contributions of Muneeb Faiq, March 2017". https://kashmirlife.net/dr-muneeb-faiq-issue-48-vol-08-133739/. 
  25. ↑ "The true cause of glaucoma and how to prevent it, Faiq Muneeb, Rima Dada, Daman Saluja, and Tanuj Dada". https://www.nutrientinsider.com/News/424/The-true-cause-of-glaucoma--and-how-to-prevent-it.htm#. 
  26. ↑ "Researchers produce evidence for glaucoma as a brain-specific diabetes". https://medicalxpress.com/news/2014-04-glaucoma-diabetes-brain.html. 
  27. ↑ "Neuroimaging and Visual Science Laboratory, New York University School of Medicine, New York, USA". https://med.nyu.edu/ophthalmology/research/neuroimaging-and-visual-science-laboratory. 
  28. ↑ "Kashmiri gets Best PhD Scholar Award at AIIMS, New Delhi, First Kashmiri to get this award". https://www.greaterkashmir.com/news/kashmir/kashmiri-gets-best-phd-scholar-award-at-aiims/. 
  29. ↑ "Kashmir Life about Muneeb Faiq". https://kashmirlife.net/dr-muneeb-faiq-issue-48-vol-08-133739/. 
  30. ↑ "First Kashmiri to get Best PhD Award-2015 at All India Institute of Medical Sciences, New Delhi". https://www.greaterkashmir.com/news/kashmir/kashmiri-gets-best-phd-scholar-award-at-aiims/. 
  31. ↑ Faiq, M. A.; Wollstein, G.; Schuman, J. S.; Chan, K. C. (2019). "Cholinergic Nervous System and Glaucoma, Muneeb Faiq, Joel Schuman,Gadi Wollstein and Kevin Chan". Progress in Retinal and Eye Research 72: 100767. doi:10.1016/j.preteyeres.2019.06.003. PMID 31242454. 
  32. ↑ "Progress in Retinal and Eye Research Vol 72 Year 2019". https://www.sciencedirect.com/science/article/pii/S1350946218300752. 
  33. ↑ "Mental Stress as a consequence and cause of vision loss, The dawn of psychosomatic ophthalmology, Bernhard A. Sabel, Jiaqi Wang, Lizbeth Cárdenas-Morales, Muneeb Faiq, Christine Heim, Biobehavioral HealthSocial Science Research Institute (SSRI), June 2018". https://pennstate.pure.elsevier.com/en/publications/mental-stress-as-consequence-and-cause-of-vision-loss-the-dawn-of. 
  34. ↑ "E-pharmacies, navigating through resistaance and skepticism, Daily News and Analysis 2019". https://www.researchgate.net/publication/327891534. 
  35. ↑ "DNA India 2019 E-pharmacy is a promising venture with around 50,000 online pharmacies worldwide". https://www.dnaindia.com/analysis/column-e-pharmacies-navigating-through-resistance-scepticism-2667887. 
  36. ↑ "Philosophical Investigations Search Results for Muneeb". http://www.philosophical-investigations.org/search?q=muneeb. 
  37. ↑ "Why Is There Something Rather Than Nothing, A philsophical perspective". http://www.the-philosopher.co.uk/2019/05/why-is-there-something-rather-than.html. 
  38. ↑ "Muneeb Faiq-Paradigm Shift". https://kashmirlife.net/body-explorer-issue-44-vol-09-164285/. 
  39. ↑ "British Philosopher Martin Cohen about Muneeb Faiq". https://books.google.com/books?id=E3vZCgAAQBAJ&pg=PT260&lpg=PT260&dq=muneeb+faiq+paradigm+shift+martin+cohen&source=bl&ots=JpaNhamGiJ&sig=ACfU3U2C4XuDWN0-4le4YKRH2V8-Hsi64A&hl=en&sa=X&ved=2ahUKEwj9mN24x8DpAhUiZjUKHRAJDccQ6AEwAHoECAsQAQ#v=onepage&q=muneeb%20faiq%20paradigm%20shift%20martin%20cohen&f=false. 
  40. ↑ "Diabetes Type 4: A Paradigm Shift in the Understanding of Glaucoma, the Brain Specific Diabetes and the Candidature of Insulin as a Therapeutic Agent. Journal-Current Molecular Medicine Volume 17 Year 2017". https://www.eurekaselect.com/149813/article. 
  41. ↑ "Doctors make a case for glaucoma as type 4 diabetes, Diabetes Queensland Australia 2017". https://www.diabetesqld.org.au/media-centre/2017/march/doctors-make-a-case-for-glaucoma-as-type-4-diabetes.aspx. 
  42. ↑ "Kashmiri Scientist Discovers new type of diabetes afflicting the brain, February 2017". https://kashmirlife.net/kashmiri-scientist-discovers-new-type-diabetes-afflicting-brain-133208/. 
  43. ↑ "Type 4 diabetes afflicts brain and eye, Deccan Chronicle 2017". https://www.deccanchronicle.com/lifestyle/health-and-wellbeing/210217/type-4-diabetes-afflicts-brain-eye-tissue-says-study.html. 
  44. ↑ "Association of Research on Vision and Ophthalmology, Annual meeting Vancouver, Canada 2019". https://www.arvo.org/globalassets/annual-meeting/program/psb/2019-psb-sunday.pdf. 
  45. ↑ "Brain as the potential diagnostic and therapeutic target for glaucoma, Journal CNS & Drug Targets, Volume 15, Issue 7, Year 2016". http://www.eurekaselect.com/140521/article. 
  46. ↑ Faiq, M. A. (2016). "Vision Restoration in Glaucoma; Nihilism and Optimism at Crossroads-Invited Editorial, Oman Journal of Ophthalmology official Journal of Oman Ophthalmology Society, Volume 9, year 2016". Oman Journal of Ophthalmology 9 (3): 123–124. doi:10.4103/0974-620X.192260. PMID 27843224. 
  47. ↑ "Video and step by step dissection of human abdomen showing mesentery to be a single entity; Journal-Colorectal Disease Year 2017". https://www.youtube.com/watch?v=pKiTUucRnFQ. 
  48. ↑ "Kashmiri scientist part of groundbreaking discovery about human body, Greater Kashmir-2017". https://www.greaterkashmir.com/news/health/kashmiri-scientist-part-of-groundbreaking-discovery-about-human-body/. 
  49. ↑ "Kashmiri scientist puts 500 year old story about human body to rest, Kashmir Observer-Cover Story 2017". https://kashmirobserver.net/2017/11/08/kashmiri-scientist-puts-500-year-old-story-about-human-body-to-rest/. 
  50. ↑ "Da-Vinci feeling was right say AIIMS doctors; Daily News and Analysis Report by Cheena Kapoor". https://www.dnaindia.com/india/report-da-vinci-gut-feeling-was-right-says-aiims-2558206. 
  51. ↑ "Detailed report and explanation about mesentery as a single entity all along the gut tube. Dynamics of a groundbreaking discovery". https://issuu.com/eedrn/docs/press_release-mesentery__dec_17.doc. 
  52. ↑ Kumar, Ashutosh; Faiq, Muneeb A.; Krishna, Hare; Kishan, Vijay; Raj, Gladwin V.; Coffey, John Calvin; Jacob, Tony George (2020). "Development of a Novel Technique to Dissect the Mesentery That Preserves Mesenteric Continuity and Enables Characterization of the ex vivo Mesentery". Frontiers in Surgery 6: 80. doi:10.3389/fsurg.2019.00080. PMID 32039231. 
  53. ↑ Kumar, A.; Singh, H. N.; Pareek, V.; Raza, K.; Dantham, S.; Kumar, P.; Mochan, S.; Faiq, M. A. (2016). "A Possible Mechanism of Zika Virus Associated Microcephaly: Imperative Role of Retinoic Acid Response Element (RARE) Consensus Sequence Repeats in the Viral Genome; Journal-Frontiers in Human Neuroscience Volume 9, Year 2016". Frontiers in Human Neuroscience 10: 403. doi:10.3389/fnhum.2016.00403. PMID 27555815. 
  54. ↑ "Scientists determine how Zika virus causes brain defects and microcephaly, Medical Express, August 2016". https://medicalxpress.com/news/2016-08-scientists-zika-virus-brain-defects.html. 
  55. ↑ "Is this how Zika virus is affecting baby brains ask Indian scientists; Portal-The Wire, August 2016". https://thewire.in/60147/is-this-how-zika-is-affecting-babies-brains-ask-indian-scientists/?fromNewsdog=1/amp. 
  56. ↑ "AIIMS New Delhi Researchers find how Zika virus may cause microcephaly". https://www.business-standard.com/article/news-ians/aiims-researchers-find-how-zika-virus-may-cause-microcephaly-116081001056_1.html. 
  57. ↑ "Business Standard; How Zika virus causes microcephaly". https://www.business-standard.com/article/news-ians/aiims-researchers-find-how-zika-virus-may-cause-microcephaly-116081001056_1.html. 
  58. ↑ "Scientists explain how Zika virus causes genome resurrection; Scientific report published in Frontiers in Microbiology Journal.". https://www.dnaindia.com/delhi/report-scientists-at-aiims-nbrc-explain-genome-resurrection-by-zika-virus-2582585. 
  59. ↑ "Mindfulness Meditation Reduces Intraocular Pressure, Lowers Stress Biomarkers and Modulates Gene Expression in Glaucoma: A Randomized Controlled Trial. Journal of Glaucoma. 27(12):1061–1067, December 2018". https://insights.ovid.com/pubmed?pmid=30256277. 
  60. ↑ "Meditation enhances brain oxygenation, upregulates BDNF and improves quality of life in patients with primary open-angle glaucoma: A randomized controlled trial. Journal; Restorative Neurology and Neuroscience, Volume 36, issue 6, Year 2018". https://content.iospress.com/articles/restorative-neurology-and-neuroscience/rnn180857. 
  61. ↑ "Meditation: An effective new therapy to reduce eye pressure in primary open-angle glaucoma. Eureka Alert-American Association for Advancement of Science, November 2018". https://www.eurekalert.org/pub_releases/2018-11/ifmp-mae110518.php. 
  62. ↑ "Meditation—an effective new therapy to reduce eye pressure in primary open-angle glaucoma by Otto-v.-Guericke Universität Magdeburg. Reported by Medical Express. November 2018". https://medicalxpress.com/news/2018-11-meditationan-effective-therapy-eye-pressure.html. 
  63. ↑ "Can meditation reduce eye pressure in primary open-angle glaucoma? 12th November 2018. Health Europa News". https://www.healtheuropa.eu/meditation-primary-open-angle-glaucoma/88927/. 
  64. ↑ "Persistent stress may lead to vision loss, study shows. Report by Medical News Today. June 2018". https://www.medicalnewstoday.com/articles/322222.php#1. 
  65. ↑ "Mental Stress Can Cause Vision Loss, Newsweek-2018". https://www.newsweek.com/mental-stress-can-cause-vision-loss-985014. 
  66. ↑ "Mental Stress Can Cause Vision Loss, Newsweek-2018". https://www.belmarrahealth.com/mindful-meditation-effective-therapy-reduce-eye-pressure-primary-open-angle-glaucoma/. 

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