Biology:Glycoprotein O-fatty-acyltransferase

From HandWiki
glycoprotein O-fatty-acyltransferase
Identifiers
EC number2.3.1.142
CAS number122191-29-1
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

In enzymology, a glycoprotein O-fatty-acyltransferase (EC 2.3.1.142) is an enzyme that catalyzes the chemical reaction

palmitoyl-CoA + mucus glycoprotein [math]\displaystyle{ \rightleftharpoons }[/math] CoA + O-palmitoylglycoprotein

Thus, the two substrates of this enzyme are palmitoyl-CoA and mucus glycoprotein, whereas its two products are CoA and O-palmitoylglycoprotein.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is fatty-acyl-CoA:mucus-glycoprotein fatty-acyltransferase. This enzyme is also called protein acyltransferase.

References

  • "Purification of protein fatty acyltransferase and determination of its distribution and topology". J. Biol. Chem. 265 (9): 5139–44. 1990. PMID 2318887.