Chemistry:Pegylated interferon

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Pegylated interferon (PEG-IFN) is a class of medication that includes three different drugs as of 2012:[1]

  • Pegylated interferon-alpha-2a
  • Pegylated interferon-alpha-2b
  • Pegylated interferon-beta-1a[2]

In these formulations, Polyethylene glycol (PEG) is added to make interferon last longer in the body.[3] They are used to treat both hepatitis B,[4] hepatitis C[1] and multiple sclerosis.[2]

Pegylated interferon is contraindicated in patients with hyperbilirubinaemia.

References




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