Medicine:Hypofractionated high-dose intensity-modulated radiotherapy

From HandWiki

This is an experimental form of intensity-modulated radiotherapy where higher X-ray dosages are used in fewer fractions (sessions) this is called hypofractionated radiotherapy. Although the dose per fraction is higher than standard radiotherapy, the total dose is lower.[1]

The hope is that it will be as effective but cause less toxicity.[1]

Prostate cancer

One trial[2] for prostate cancer ran in 2011.[1]In 2016 the HYPRO study reported results comparing the use of standard fractionation (39 fractions of 2 Gy for 8 weeks) with hypofractionation (with 19 fractions of 3.4 Gy for 6.5 weeks) among 820 patients with intermediate- or high-risk prostate cancer.[3]

References

  1. ↑ 1.0 1.1 1.2 "A trial comparing different ways of giving radiotherapy for prostate cancer (CHHIP)". 2015-03-17. http://www.cancerresearchuk.org/about-cancer/find-a-clinical-trial/a-trial-comparing-different-ways-of-giving-radiotherapy-for-prostate-cancer#undefined. 
  2. ↑ UKCRN Database:Conventional or Hypofractionated High Dose Intensity Modulated Radiotherapy for Prostate Cancer
  3. ↑ Toxicities May Affect Readiness of Hypofractionation in Prostate Cancer. March 2016





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