Biology:Trans-2,3-dihydro-3-hydroxyanthranilate isomerase
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Trans-2,3-dihydro-3-hydroxyanthranilate isomerase | |||||||||
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Identifiers | |||||||||
EC number | 5.3.3.17 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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Trans-2,3-dihydro-3-hydroxyanthranilate isomerase (EC 5.3.3.17, phzF (gene)) is an enzyme with systematic name (5S,6S)-6-amino-5-hydroxycyclohexane-1,3-diene-1-carboxyate isomerase.[1][2][3][4][5] This enzyme catalyses the following chemical reaction
- (5S,6S)-6-amino-5-hydroxycyclohexane-1,3-diene-1-carboxyate [math]\displaystyle{ \rightleftharpoons }[/math] (1R,6S)-6-amino-5-oxocyclohex-2-ene-1-carboxylate
The enzyme is involved in phenazine biosynthesis.
References
- ↑ "Structure and function of the phenazine biosynthesis protein PhzF from Pseudomonas fluorescens 2-79". Biochemistry 43 (39): 12427–35. October 2004. doi:10.1021/bi049059z. PMID 15449932.
- ↑ "Structure and function of the phenazine biosynthetic protein PhzF from Pseudomonas fluorescens". Proceedings of the National Academy of Sciences of the United States of America 101 (47): 16431–6. November 2004. doi:10.1073/pnas.0407371101. PMID 15545603.
- ↑ "Structure of the phenazine biosynthesis enzyme PhzG". Acta Crystallographica Section D 60 (Pt 11): 2110–3. November 2004. doi:10.1107/s0907444904022474. PMID 15502343. http://journals.iucr.org/d/issues/2004/11/00/hm5022/hm5022.pdf.
- ↑ "The purification, crystallization and preliminary structural characterization of PhzF, a key enzyme in the phenazine-biosynthesis pathway from Pseudomonas fluorescens 2-79". Acta Crystallographica Section D 60 (Pt 1): 184–6. January 2004. doi:10.1107/s090744490302571x. PMID 14684924.
- ↑ "PhzA/B catalyzes the formation of the tricycle in phenazine biosynthesis". Journal of the American Chemical Society 130 (50): 17053–61. December 2008. doi:10.1021/ja806325k. PMID 19053436.
External links
- Trans-2,3-dihydro-3-hydroxyanthranilate+isomerase at the US National Library of Medicine Medical Subject Headings (MeSH)
Original source: https://en.wikipedia.org/wiki/Trans-2,3-dihydro-3-hydroxyanthranilate isomerase.
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