Biology:Exoribonuclease H
From HandWiki
| Exoribonuclease H | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 3.1.13.2 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Exoribonuclease H (EC 3.1.13.2) is an enzyme.[1] This enzyme catalyses the following chemical reaction
- 3'-end directed exonucleolytic cleavage of viral RNA-DNA hybrid
This is a secondary reaction to the RNA 5'-end directed cleavage 13-19 nucleotides from the RNA end performed by EC 3.1.26.13 (retroviral ribonuclease H).
References
- ↑ "HIV-1 RT-associated ribonuclease H displays both endonuclease and 3'----5' exonuclease activity". The EMBO Journal 9 (4): 1171–6. April 1990. PMID 1691093.
External links
- Exoribonuclease+H at the US National Library of Medicine Medical Subject Headings (MeSH)
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