Biology:ADP-dependent NAD(P)H-hydrate dehydratase
From HandWiki
| ADP-dependent NAD(P)H-hydrate dehydratase | |||||||||
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| Identifiers | |||||||||
| EC number | 4.2.1.136 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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ADP-dependent NAD(P)H-hydrate dehydratase (EC 4.2.1.136, (6S)-β-6-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine-dinucleotide hydro-lyase (ADP-hydrolysing), (6S)-6-β-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine-dinucleotide hydro-lyase (ADP-hydrolysing, NADH-forming)) is an enzyme with systematic name (6S)-6β-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine-dinucleotide hydro-lyase (ADP-hydrolysing; NADH-forming).[1] This enzyme catalyses the following chemical reaction
- (1) ADP + (6S)-6β-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine dinucleotide [math]\displaystyle{ \rightleftharpoons }[/math] AMP + phosphate + NADH
- (2) ADP + (6S)-6β-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine dinucleotide phosphate [math]\displaystyle{ \rightleftharpoons }[/math] AMP + phosphate + NADPH
This enzyme acts equally well on hydrated NADH and hydrated NADPH.
References
- ↑ "Extremely conserved ATP- or ADP-dependent enzymatic system for nicotinamide nucleotide repair". The Journal of Biological Chemistry 286 (48): 41246–52. December 2011. doi:10.1074/jbc.c111.310847. PMID 21994945.
External links
- ADP-dependent+NAD(P)H-hydrate+dehydratase at the US National Library of Medicine Medical Subject Headings (MeSH)
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