Chemistry:Dibrospidium chloride
From HandWiki
Short description: Cancer drug being studied
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| Other names | Spirobromin, spirobromine |
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| Formula | C18-H32-Br2-N4-O2.2Cl |
| Molar mass | 567.191 |
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Dibrospidium chloride, also known as spirobromin, is a drug being investigated to treat bone cancer. It has potential anti-inflammatory and anti-neoplastic properties. It is an alkylating antineoplastic agent.[1][2]
Dibrospidium chloride and related compounds were developed in Russia in the 1980s.[3][4] It is currently used in Russia as a cytostatic antitumor chemotherapeutic drug.[5]
References
- ↑ "CAS - 86641-76-1 - CURYRIVJTBNEGU-UHFFFAOYSA-L - Dibrospidium chloride [INN"] (in en). ChemIDplus. U.S. National Library of Medicine. https://chem.nlm.nih.gov/chemidplus/rn/86641-76-1.
- ↑ "Dibrospidium Chloride" (in en). PubChem. U.S. National Library of Medicine. https://pubchem.ncbi.nlm.nih.gov/compound/72114.
- ↑ "New antitumor agent — Spirobromin". Pharmaceutical Chemistry Journal 17 (5): 375–377. 1983. doi:10.1007/BF00765650.
- ↑ "Dependence of the antitumor activity of spirobromin analogs on their structure". Pharmaceutical Chemistry Journal 18 (12): 803–806. 1984. doi:10.1007/BF00768330.
- ↑ "Dispirotripiperazine-core compounds, their biological activity with a focus on broad antiviral property, and perspectives in drug design (mini-review)". European Journal of Medicinal Chemistry 211: 113014. February 2021. doi:10.1016/j.ejmech.2020.113014. PMID 33218683.
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