https://handwiki.org/wiki/index.php?title=Biology:Berkeley_body&feed=atom&action=historyBiology:Berkeley body - Revision history2024-03-28T11:36:58ZRevision history for this page on the wikiMediaWiki 1.38.4https://handwiki.org/wiki/index.php?title=Biology:Berkeley_body&diff=2790652&oldid=prevWikiGary: fixing2023-03-11T00:13:34Z<p>fixing</p>
<p><b>New page</b></p><div>{{Short description|Organelle unique to Saccharomyces cerevisiae}}<br />
'''Berkeley bodies''' are [[Biology:Organelle|organelle]]s unique to the yeast cell ''[[Biology:Saccharomyces cerevisiae|Saccharomyces cerevisiae]]'', with a secretory mutation in the genes [[Biology:ARFGEF2|sec7]] and sec14. The function of the organelle lies in the CTV (cytoplasm to vacuole targeting) pathway, which is a transport pathway for certain vacuolar hydrolases to be degenerated. The Berkeley body acts as the transport medium from the [[Biology:Cytoplasm|cytoplasm]] to the [[Biology:Vacuole|vacuole]] within this pathway. Studies have shown that Berkeley bodies share structural similarities with autophagosomes, which are involved in [[Biology:Autophagy|autophagy]].<ref>Fulvio Reggiori, Chao-Wen Wang, Usha Nair, Takahiro Shintani, Hagai Abeliovich, and Daniel J. Klionsky, ''Early Stages of the Secretory Pathway, but Not Endosomes, Are Required for Cvt Vesicle and Autophagosome Assembly in Saccharomyces cerevisiae'', from Molecular Biology of the Cell Vol. 15, 2189–2204, May 2004.</ref><br />
<br />
The organelle consists of two enclosed membranes forming an enclosed [[Biology:Lumen (anatomy)|lumen]], which contains cytoplasm. It is formed by vesicles budding off the [[Biology:Golgi apparatus|Golgi apparatus]] or the endoplasmic reticulum. They were discovered in 1980 by Peter Novick and [[Biography:Randy Schekman|Randy Schekman]], of the Department of Biochemistry, [[Organization:University of California, Berkeley|University of California, Berkeley]].<ref>Peter Novick, Charles Field and Randy Schekman. Identification of 23 Complementation Groups Required for Post-translational Events in the Yeast Secretory Pathway. ''Cell'', Vol. 21, 205–215, August, 1980.</ref><br />
<br />
== References ==<br />
<references/><br />
<br />
[[Category:Organelles]]<br />
[[Category:Saccharomyces cerevisiae]]<br />
<br />
<br />
<br />
{{Sourceattribution|Berkeley body}}</div>WikiGary