Biology:ZP1

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Short description: Protein-coding gene in the species Homo sapiens

Zona pellucida sperm-binding protein 1 is a protein that cross-links ZP2 and ZP3. Aberrant ZP1 results in sequestration of ZP3 in the cytoplasm, thereby preventing the formation of the zona pellucida around the oocyte.[1]

References

  1. ↑ Huang, Hua-Lin; Lv, Chao; Zhao, Ying-Chun; Li, Wen; He, Xue-Mei; Li, Ping; Sha, Ai-Guo; Tian, Xiao et al. (2014). "Mutant ZP1 in Familial Infertility". New England Journal of Medicine 370 (13): 1220–1226. doi:10.1056/NEJMoa1308851. ISSN 0028-4793. PMID 24670168. 



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