Biology:SL2 RNA

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SL2 RNA
RF00199.jpg
Predicted secondary structure and sequence conservation of SL2
Identifiers
SymbolSL2
RfamRF00199
Other data
RNA typeGene
Domain(s)Eukaryota
GO0000365
SO0000233
PDB structuresPDBe

SL2 RNA is a non-coding RNA involved in trans splicing in lower eukaryotes. Trans-splicing is a form of RNA processing. The acquisition of a spliced leader from an SL RNA is an inter-molecular reaction which precisely joins exons derived from separately transcribed RNAs.[1] Approximately 25% of C. elegans genes are organised into polycistronic transcription units and the presence of SL2 on an mRNA is an indication the gene is in an operon.[2]

References

  1. "Trans-spliced leader RNA, 5S-rRNA genes and novel variant orphan spliced-leader of the lymphatic filarial nematode Wuchereria bancrofti, and a sensitive polymerase chain reaction based detection assay". Gene 269 (1-2): 185–193. May 2001. doi:10.1016/S0378-1119(01)00438-3. PMID 11376950. 
  2. "trans splicing of polycistronic Caenorhabditis elegans pre-mRNAs: analysis of the SL2 RNA". Molecular and Cellular Biology 20 (18): 6659–6667. September 2000. doi:10.1128/MCB.20.18.6659-6667.2000. PMID 10958663. 

External links