Chemistry:3-Hydroxyoctanoic acid

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3-Hydroxyoctanoic acid
3-hydroxyoctanoic acid.svg
Names
Preferred IUPAC name
3-Hydroxyoctanoic acid
Other names
3-Hydroxycaprylic acid; β-Hydroxyoctanoic acid
Identifiers
3D model (JSmol)
ChEBI
ChemSpider
MeSH C101940
UNII
Properties
C8H16O3
Molar mass 160.213 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references
Tracking categories (test):

3-Hydroxyoctanoic acid is a beta-hydroxy acid that is naturally produced in humans, other animals, and plants.

3-Hydroxyoctanoic acid is the primary endogenous agonist of hydroxycarboxylic acid receptor 3 (HCA3), a G protein-coupled receptor protein which is encoded by the human gene HCAR3.[1][2] In plants, signalling chemical emitted by the orchid Cymbidium floribundum and recognized by Japanese honeybees (Apis cerana japonica).[3]

References

  1. Offermanns, S; Colletti, S. L; Lovenberg, T. W; Semple, G; Wise, A; Ijzerman, A. P (June 2011). "International Union of Basic and Clinical Pharmacology. LXXXII: Nomenclature and Classification of Hydroxy-carboxylic Acid Receptors (GPR81, GPR109A, and GPR109B)". Pharmacological Reviews 63 (2): 269–90. doi:10.1124/pr.110.003301. PMID 21454438. 
  2. Offermanns, S.; Colletti, S. L.; IJzerman, A. P.; Lovenberg, T. W.; Semple, G.; Wise, A.; Waters, M. G.; ((CGTP Collaborators)). Hydroxycarboxylic acid receptors. International Union of Basic and Clinical Pharmacology. http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=48. Retrieved 13 July 2018. 
  3. Sugahara, M; Izutsu, K; Nishimura, Y; Sakamoto, F (2013). "Oriental orchid (Cymbidium floribundum) attracts the Japanese honeybee (Apis cerana japonica) with a mixture of 3-hydroxyoctanoic acid and 10-hydroxy- (E)-2-decenoic acid". Zoological Science 30 (2): 99–104. doi:10.2108/zsj.30.99. PMID 23387843.