Biology:NPM3
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Nucleoplasmin-3 is a protein that in humans is encoded by the NPM3 gene.[1][2]
The protein encoded by this gene is related to the nuclear chaperone phosphoproteins, nucleoplasmin and nucleophosmin. It is highly homologous to the murine Npm3 gene. Based on the structural similarity of the human NPM3 gene product to nucleoplasmin and nucleophosmin, NPM3 may represent a new member of this gene family, and may share basic functions with the molecular chaperones.[2]
References
- ↑ "Cloning, expression and nuclear localization of human NPM3, a member of the nucleophosmin/nucleoplasmin family of nuclear chaperones". BMC Genomics 2: 8. Jul 2003. doi:10.1186/1471-2164-2-8. PMID 11722795.
- ↑ 2.0 2.1 "Entrez Gene: NPM3 nucleophosmin/nucleoplasmin, 3". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10360.
Further reading
- "Nuclear chaperones.". Semin. Cell Dev. Biol. 11 (1): 7–14. 2000. doi:10.1006/scdb.1999.0346. PMID 10736259.
- "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635–48. 2006. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
- "Nucleolar proteome dynamics.". Nature 433 (7021): 77–83. 2005. doi:10.1038/nature03207. PMID 15635413.
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. 2004. doi:10.1101/gr.2596504. PMID 15489334.
- "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. 2003. doi:10.1073/pnas.242603899. PMID 12477932.
- "Directed proteomic analysis of the human nucleolus.". Curr. Biol. 12 (1): 1–11. 2002. doi:10.1016/S0960-9822(01)00650-9. PMID 11790298.
- "Npm3: a novel, widely expressed gene encoding a protein related to the molecular chaperones nucleoplasmin and nucleophosmin.". Genomics 42 (1): 137–40. 1997. doi:10.1006/geno.1997.4353. PMID 9177783.
External links
- NPM3 human gene location in the UCSC Genome Browser.
- NPM3 human gene details in the UCSC Genome Browser.