Chemistry:Benzamidenafil

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Benzamidenafil
Benzamidenafil.svg
Names
Preferred IUPAC name
N-[(3,4-Dimethoxyphenyl)methyl]-2-[(1-hydroxypropan-2-yl)amino]-5-nitrobenzamide
Other names
Xanthoanthrafil
Identifiers
3D model (JSmol)
ChemSpider
MeSH C442640
UNII
Properties
C19H23N3O6
Molar mass 389.408 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references
Tracking categories (test):

Benzamidenafil or xanthoanthrafil is a synthetic drug that acts as a PDE5 inhibitor. It has the same mechanism of action as pharmaceutical drugs used to treat erectile dysfunction,[1] but it is not approved by any regulatory agency for such use. It has been found as an undeclared adulterant in supposedly "natural" health supplements.[1] In 2009, the supplement manufacturer Hi-Tech Pharmaceuticals recalled its product Stamina-Rx because it was adulterated with benzamidenafil.[2]

References

  1. 1.0 1.1 Zou, Peng; Hou, Peiling; Oh, Sharon Sze-Yin; Ge, Xiaowei; Bloodworth, Bosco Chen; Low, Min-Yong; Koh, Hwee-Ling (2008). "Identification of benzamidenafil, a new class of phosphodiesterase-5 inhibitor, as an adulterant in a dietary supplement". Journal of Pharmaceutical and Biomedical Analysis 47 (2): 255–259. doi:10.1016/j.jpba.2008.01.004. PMID 18280079. 
  2. Miranda Hitti. "Stamina-Rx Supplements Recalled" (in en). https://www.webmd.com/erectile-dysfunction/news/20090617/stamina-rx-supplements-recalled.