Chemistry:Isay reaction

From HandWiki
Isay reaction
Named after Oskar Isay
Reaction type Ring forming reaction

The Isay reaction also known as Gabriel-Isay condensation is an organic reaction in which certain diaminopyrimidines are transformed into pterins by condensation with a 1,2-dicarbonyl compound, such as 2,3-butanedione.[1][2] The reaction is named after Oskar Isay.

See also

References

  1. Isay, Oskar (1906). "Eine Synthese des Purins". Berichte der Deutschen Chemischen Gesellschaft 39: 250–265. doi:10.1002/cber.19060390149. https://zenodo.org/record/1426174. .
  2. Kaufman, Seymour; Storm, Carlyle B.; Shiman, Ross (1971). "Preparation of 6-substituted pterins via the Isay reaction". The Journal of Organic Chemistry 36 (25): 3925–3927. doi:10.1021/jo00824a016. .