Chemistry:Norgestomet

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Short description: Chemical compound
Norgestomet
Norgestomet.svg
Clinical data
Trade namesSyncro-Mate B, Crestar
Other namesNorgestamet; SC-21009; 11β-Methyl-17α-acetoxy-19-norprogesterone; 17α-Hydroxy-11β-methyl-19-norpregn-4-ene-3,20-dione acetate
Drug classProgestogen; Progestin; Progestogen ester
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
Chemical and physical data
FormulaC23H32O4
Molar mass372.505 g·mol−1
3D model (JSmol)

Norgestomet, or norgestamet, sold under the brand name Syncro-Mate B and Crestar, is a progestin medication which is used in veterinary medicine to control estrus and ovulation in cattle.[1][2]

Uses

Veterinary

Norgestomet is used in veterinary medicine.

Pharmacology

Pharmacodynamics

Norgestomet is a progestogen. In addition to the progesterone receptor, it possesses weak (micromolar) affinity for the glucocorticoid receptor.[3]

Chemistry

Norgestomet, also known as 11β-methyl-17α-acetoxy-19-norprogesterone or as 17α-hydroxy-11β-methyl-19-norpregn-4-ene-3,20-dione acetate, is a synthetic norpregnane steroid and a derivative of progesterone.[1][4]

History

Norgestomet was developed and introduced for veterinary use in the mid-1970s.[5]

Society and culture

Generic names

Norgestomet is the generic name of the drug and its INN, USAN, and BAN.[1][4] It also known as norgestamet and is known by its developmental code name SC-21009.[1][4][6]

Brand names

Norgestomet is marketed under the brand names Syncro-Mate B and Crestar.[1][4]

References