Chemistry:Revaprazan

From HandWiki
Short description: Chemical compound
Revaprazan
Revaprazan.svg
Clinical data
Trade namesRevanex[1]
Other namesYH1885
ATC code
  • None
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
Chemical and physical data
FormulaC22H23FN4
Molar mass362.452 g·mol−1
3D model (JSmol)

Revaprazan (trade name Revanex) is a drug that reduces gastric acid secretion which is used for the treatment of gastritis.[2] It acts as an acid pump antagonist[3] (potassium-competitive acid blocker). Revaprazan is approved for use in South Korea,[4] but is not approved in Europe or the United States.

References

  1. "Revaprazan". drugs.com. https://www.drugs.com/international/revaprazan.html. 
  2. "Clinical trial: inhibitory effect of revaprazan on gastric acid secretion in healthy male subjects". J Gastroenterol Hepatol 25 (10): 1618–1625. Oct 2010. doi:10.1111/j.1440-1746.2010.06408.x. PMID 20880169. 
  3. "Pharmacokinetic and pharmacodynamic evaluation of a novel proton pump inhibitor, YH1885, in healthy volunteers". J Clin Pharmacol 44 (1): 73–82. Jan 2004. doi:10.1177/0091270003261321. PMID 14681344. 
  4. "Revaprazan Yuhan registered, South Korea (gastritis)". R & D Focus Drug News. September 25, 2006. http://business.highbeam.com/436989/article-1G1-151758768/revaprazan-yuhan-registered-south-korea.