Biology:Beta-defensin 3

From HandWiki
Short description: Protein


A representation of the 3D structure of the protein myoglobin showing turquoise α-helices.
Generic protein structure example

Beta-defensin 3 is a protein that in humans is encoded by the DEFB3 gene.[1]

HBD-3 was first isolated from human lesional psoriatic scales. RT-PCR showed HBD-3 to be expressed highly in skin, trachea, tongue and tonsils, with lower levels found salivary glands, uterus, kidney, bone marrow, thymus, colon, stomach, adenoid, pharynx, and larynx.[2]

References

  1. "hBD-1: a novel beta-defensin from human plasma". FEBS Letters 368 (2): 331–5. July 1995. doi:10.1016/0014-5793(95)00687-5. PMID 7628632. 
  2. "The human beta-defensin-3, an antibacterial peptide with multiple biological functions". Biochimica et Biophysica Acta (BBA) - Biomembranes 1758 (9): 1499–512. September 2006. doi:10.1016/j.bbamem.2006.07.007. PMID 16978580.