Blast2GO

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Short description: Bioinformatics software tool
Blast2GO
Blast2GO Logo.png
Blast2GO
TypeBioinformatics Software
Inception2011 (2011)
ManufacturerBioBam Bioinformatics
Models madeDemo, Basic, Trial, Pro, Plugin, Commandline
Websitehttps://www.blast2go.com

Blast2GO, first published in 2005,[1][2][3][4] is a bioinformatics software tool for the automatic, high-throughput functional annotation of novel sequence data (genes proteins). It makes use of the BLAST[5] algorithm to identify similar sequences to then transfers existing functional annotation from yet characterised sequences to the novel one. The functional information is represented via the Gene Ontology (GO), a controlled vocabulary of functional attributes.[citation needed] The Gene Ontology, or GO, is a major bioinformatics initiative to unify the representation of gene and gene product attributes across all species.[6]

See also

References

  1. Conesa, A; Götz, S; García-Gómez, JM; Terol, J; Talón, M; Robles, M (Sep 15, 2005). "Blast2GO: a universal tool for annotation, visualization and analysis in functional genomics research.". Bioinformatics 21 (18): 3674–6. doi:10.1093/bioinformatics/bti610. PMID 16081474. 
  2. Götz, S; García-Gómez, JM; Terol, J; Williams, TD; Nagaraj, SH; Nueda, MJ; Robles, M; Talón, M et al. (June 2008). "High-throughput functional annotation and data mining with the Blast2GO suite". Nucleic Acids Research 36 (10): 3420–35. doi:10.1093/nar/gkn176. PMID 18445632. 
  3. Conesa, A; Götz, S (2008). "Blast2GO: A comprehensive suite for functional analysis in plant genomics". International Journal of Plant Genomics 2008: 1–12. doi:10.1155/2008/619832. PMID 18483572. 
  4. Götz, S; Arnold, R; Sebastián-León, P; Martín-Rodríguez, S; Tischler, P; Jehl, MA; Dopazo, J; Rattei, T et al. (Apr 1, 2011). "B2G-FAR, a species-centered GO annotation repository". Bioinformatics 27 (7): 919–24. doi:10.1093/bioinformatics/btr059. PMID 21335611. 
  5. Altschul, SF; Gish, W; Miller, W; Myers, EW; Lipman, DJ (Oct 5, 1990). "Basic local alignment search tool". Journal of Molecular Biology 215 (3): 403–10. doi:10.1016/S0022-2836(05)80360-2. PMID 2231712. 
  6. The Gene Ontology Consortium (January 2008). "The Gene Ontology project in 2008". Nucleic Acids Res. 36 (Database issue): D440–4. doi:10.1093/nar/gkm883. PMID 17984083. 

External links

  • Blast2GO - Tool for functional annotation of (novel) sequences and the analysis of annotation data.
  • Company developing Blast2GO — BioBam Bioinformatics S.L., a bioinformatics company dedicated to creating user-friendly software for the scientific community is developing, maintaining and distributing Blast2GO.
  • Gene Ontology Tools — Provides access to the ontologies, software tools, annotated gene product lists, and reference documents describing the GO and its uses.
  • PlantRegMap —Plant GO annotation for 165 species and GO enrichment analysis