Chemistry:Monacolin J
From HandWiki
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| Preferred IUPAC name
(4R,6R)-4-Hydroxy-6-{2-[(1S,2S,6R,8S,8aR)-8-hydroxy-2,6-dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]ethyl}oxan-2-one | |
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3D model (JSmol)
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PubChem CID
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| Properties | |
| C19H28O4 | |
| Molar mass | 320.429 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
| Infobox references | |
Monacolin J is a statin made by red yeast rice. Monacolin J is a precursor to simvastatin and has potential neuroprotective activities.[1][unreliable medical source?]
It can be produced by total mycosynthesis.
References
- ↑ Campoy, Sonia; Sierra, Saleta; Suarez, Beatriz; Ramos, Maria C.; Velasco, Javier; Burgos, Javier S.; Adrio, Jose L. (August 2010). "Semisynthesis of novel monacolin J derivatives: hypocholesterolemic and neuroprotective activities". J. Antibiot. 63 (8): 499–505. doi:10.1038/ja.2010.76. PMID 20648024.
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