Biology:Thiosulfate—thiol sulfurtransferase
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Short description: Class of enzymes
| Thiosulfate-thiol sulfurtransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.8.1.3 | ||||||||
| CAS number | 111070-24-7 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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Thiosulfate-thiol sulfurtransferase (EC 2.8.1.3) is an enzyme that catalyzes the chemical reaction
- REDIRECT Template:Chemical reaction
The enzyme characterised from Thiobacillus thioparus converts thiosulfate to sulfite and hydrogen sulfide by reaction with two units of glutathione, which is dimerised to glutathione disulfide.[1] The enzyme has also been found in carp liver and yeast.[2][3]
This enzyme is a transferases, specifically a sulfurtransferases, which transfer sulfur-containing groups. The systematic name of this enzyme class is thiosulfate:thiol sulfurtransferase. Other names in common use include glutathione-dependent thiosulfate reductase, sulfane reductase, and sulfane sulfurtransferase.[4]
References
- ↑ "The oxidation of thiosulfate and phosphorylation in extracts of Thiobacillus thioparus". J. Biol. Chem. 237: 190–7. 1962. doi:10.1016/S0021-9258(18)81384-9. PMID 14484816.
- ↑ Sido B; Koj A (1972). "Separation of rhodanese and thiosulfate reductase activities in carp liver extracts". Acta Biol. Cracow Ser. Zool. 15: 97–103.
- ↑ "Purification and steady-state kinetic analysis of yeast thiosulfate reductase". Arch. Biochem. Biophys. 195 (1): 211–22. 1979. doi:10.1016/0003-9861(79)90343-6. PMID 383018.
- ↑ Enzyme 2.8.1.3 at KEGG Pathway Database.
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