Chemistry:7α-Methyl-19-norandrostenedione

From HandWiki

7α-Methyl-19-norandrostenedione (MENT dione), or 7α-methyl-19-norandrost-4-ene-3,17-dione, also known as trestione, as well as 7α-methylestr-4-ene-3,17-dione, is a synthetic anabolic-androgenic steroid (AAS) and a derivative of 19-nortestosterone (nandrolone).[1][2] It may act as a prohormone of trestolone (7α-methyl-19-nortestosterone; MENT).[1][2] MENT dione has been sold on the Internet under the name Mentabolan as a "dietary supplement".[1][2]

Applications

  1. If mentabolan is oxidized with a catalytic amount of a copper halide in the presence of oxygen it gives almestrone.[3]
  2. Mentabolan is a precursor in a recent Chinese synthesis of tibolone.[4]
  3. Mentabolan was an intermediate in the original Upjohn synthesis of mibolerone.

See also

References

  1. 1.0 1.1 1.2 "Designer steroids - over-the-counter supplements and their androgenic component: review of an increasing problem". Andrology 3 (2): 150–5. 2015. doi:10.1111/andr.307. PMID 25684733. 
  2. 2.0 2.1 2.2 Na, S., Yum, T., Choi, H., Jung, H., Pang, K., & Kim, Y. (2012). Detection of metabolites of mentabolan, a pro-anabolic steroid never marketed, in human urine by GC/MS and GC/MS/MS analysis. 제 49 회 한국분석과학회 추계학술대회, 229-229.
  3. Kuniaki Tatsuta, Kazuo Maruhashi, & Shingo Yano, WO2007049672 (to Taiho Pharmaceutical Co Ltd).
  4. 孙晓明, et al. CN114409717 (2023 to Hunan Keyixin Biomedical Co ltd).