File:41598 2024 79564 Fig1 HTML.webp

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Description
English: Identification of differentially expressed genes between all hyperthyroid (HT) and euthyroid (ET) samples. (a) Photographs of clinically hyperthyroid cats, with the unkempt coat and lean appearance observed in some FHT cases. (b) Principal component analysis of euthyroid (ET) and hyperthyroid RNA-seq samples from both treated (HT-T) and untreated (HT-U) cats. (c) Volcano plot showing differentially expressed genes (adjusted p < 0.05) with higher expression in ET (blue) or HT (red) samples. Grey points represent genes with no significant difference in expression between groups (adjusted p > 0.05). (d) and (e) Enriched Gene Ontology (GO) Biological Process terms for genes with higher expression in (d) HT samples and (e) ET samples.
Date 20 November 2024
Source https://www.nature.com/articles/s41598-024-79564-z
Author Thomas K. Hiron, Joana Aguiar, Jonathan M. Williams, Sara Falcone, Paul A. Norman, Jonathan Elliott, Robert C. Fowkes, Harriet M. Syme & Lucy J. Davison

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Figures from a study on feline hyperthyroidism

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20 November 2024

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