File:EZHIP expression in diffuse midline gliomas.webp

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Summary

Description
English: A distinct H3K27me3 loss (A, magnification, ×400) in one case of diffuse midline glioma with EZHIP overexpression, without expression of H3K27-mutant protein (B, magnification, ×400) and with strong positive EZHIP expression (C, magnification, ×400). A case of diffuse midline glioma, H3K27-mutant with a loss of expression of H3K27me3 (D, magnification, ×400), nuclear expression of H3K27-mutant protein (E, magnification, ×400), and without expression of EZHIP (F, magnification, ×400). DMG diffuse midline glioma, WT wildtype. Black scale bars represent 50 μm
Date
Source https://actaneurocomms.biomedcentral.com/articles/10.1186/s40478-020-01056-8
Author Antin, C., Tauziède-Espariat, A., Debily, MA. et al.

Taken from: Antin, C., Tauziède-Espariat, A., Debily, MA. et al. EZHIP is a specific diagnostic biomarker for posterior fossa ependymomas, group PFA and diffuse midline gliomas H3-WT with EZHIP overexpression. acta neuropathol commun 8, 183 (2020). https://doi.org/10.1186/s40478-020-01056-8

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EZHIP expression in diffuse midline gliomas

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5 November 2020

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848 pixel

1,960 pixel

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