View source for Biology:(2,2,3-Trimethyl-5-oxocyclopent-3-enyl)acetyl-CoA 1,5-monooxygenase

{{Short description|Class of enzymes}}
{{Infobox enzyme
| Name       = (2,2,3-Trimethyl-5-oxocyclopent-3-enyl)acetyl-CoA 1,5-monooxygenase
| EC_number  = 1.14.13.160
| CAS_number =
| GO_code    = 
| image      = 
| width      = 
| caption    =  
}}
'''(2,2,3-Trimethyl-5-oxocyclopent-3-enyl)acetyl-CoA 1,5-monooxygenase''' ({{EC number|1.14.13.160}}, ''2-oxo-Delta3-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase'', ''2-oxo-Delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase'', ''OTEMO'') is an [[Biology:Enzyme|enzyme]] with [[Biology:List of enzymes|systematic name]] ''((1R)-2,2,3-trimethyl-5-oxocyclopent-3-enyl)acetyl-CoA,NADPH:oxygen oxidoreductase (1,5-lactonizing)''.<ref>{{cite journal | vauthors = Ougham HJ, Taylor DG, Trudgill PW | title = Camphor revisited: involvement of a unique monooxygenase in metabolism of 2-oxo-delta 3-4,5,5-trimethylcyclopentenylacetic acid by Pseudomonas putida | journal = Journal of Bacteriology | volume = 153 | issue = 1 | pages = 140–52 | date = January 1983 | pmid = 6848481 | pmc = 217351 }}</ref><ref>{{cite journal | vauthors = Leisch H, Shi R, Grosse S, Morley K, Bergeron H, Cygler M, Iwaki H, Hasegawa Y, Lau PC | title = Cloning, Baeyer-Villiger biooxidations, and structures of the camphor pathway 2-oxo-Δ(3)-4,5,5-trimethylcyclopentenylacetyl-coenzyme A monooxygenase of Pseudomonas putida ATCC 17453 | journal = Applied and Environmental Microbiology | volume = 78 | issue = 7 | pages = 2200–12 | date = April 2012 | pmid = 22267661 | pmc = 3302634 | doi = 10.1128/AEM.07694-11 }}</ref><ref>{{cite journal | vauthors = Kadow M, Loschinski K, Sass S, Schmidt M, Bornscheuer UT | title = Completing the series of BVMOs involved in camphor metabolism of Pseudomonas putida NCIMB 10007 by identification of the two missing genes, their functional expression in E. coli, and biochemical characterization | journal = Applied Microbiology and Biotechnology | volume = 96 | issue = 2 | pages = 419–29 | date = October 2012 | pmid = 22286514 | doi = 10.1007/s00253-011-3859-1 }}</ref> This enzyme [[Chemistry:Catalysis|catalyses]] the following [[Chemistry:Chemical reaction|chemical reaction]]

: [(1R)-2,2,3-trimethyl-5-oxocyclopent-3-enyl]acetyl-CoA + O<sub>2</sub> + NADPH + H<sup>+</sup> <math>\rightleftharpoons</math> [(2R)-3,3,4-trimethyl-6-oxo-3,6-dihydro-1H-pyran-2-yl]acetyl-CoA + NADP<sup>+</sup> + H<sub>2</sub>O

(2,2,3-trimethyl-5-oxocyclopent-3-enyl)acetyl-CoA 1,5-monooxygenase is FAD dependent enzyme isolated from ''[[Biology:Pseudomonas putida|Pseudomonas putida]]''.

== References ==
{{reflist}}

== External links ==
* {{MeshName|(2,2,3-trimethyl-5-oxocyclopent-3-enyl)acetyl-CoA+1,5-monooxygenase}}

{{Dioxygenases}}
{{Enzymes}}

[[Category:EC 1.14.13]]

{{Sourceattribution|(2,2,3-Trimethyl-5-oxocyclopent-3-enyl)acetyl-CoA 1,5-monooxygenase}}