View source for Biology:2-amino-5-formylamino-6-ribosylaminopyrimidin-4(3H)-one 5'-monophosphate deformylase

{{Short description|Class of enzymes}}
{{Infobox enzyme
| Name       = 2-amino-5-formylamino-6-ribosylaminopyrimidin-4(3H)-one 5'-monophosphate deformylase
| EC_number  = 3.5.1.102
| CAS_number =
| GO_code    = 
| image      = 
| width      = 
| caption    =  
}}
'''2-amino-5-formylamino-6-ribosylaminopyrimidin-4(3H)-one 5'-monophosphate deformylase''' ({{EC number|3.5.1.102}}, ''ArfB'') is an [[Biology:Enzyme|enzyme]] with [[Biology:List of enzymes|systematic name]] ''2-amino-5-formylamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one amidohydrolase''.<ref>{{cite journal | vauthors = Grochowski LL, Xu H, White RH | title = An iron(II) dependent formamide hydrolase catalyzes the second step in the archaeal biosynthetic pathway to riboflavin and 7,8-didemethyl-8-hydroxy-5-deazariboflavin | journal = Biochemistry | volume = 48 | issue = 19 | pages = 4181–8 | date = May 2009 | pmid = 19309161 | doi = 10.1021/bi802341p }}</ref> This enzyme [[Chemistry:Catalysis|catalyses]] the following [[Chemistry:Chemical reaction|chemical reaction]]

: [[Chemistry:2-Amino-5-formylamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one|2-Amino-5-formylamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one]] + H<sub>2</sub>O <math>\rightleftharpoons</math> 2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one + [[Chemistry:Formate|formate]]

The enzyme catalyses the second step in archaeal [[Biology:Riboflavin|riboflavin]] and 7,8-didemethyl-8-hydroxy-5-deazariboflavin [[Biology:Biosynthesis|biosynthesis]].

== References ==
{{reflist}}

== External links ==
* {{MeshName|2-amino-5-formylamino-6-ribosylaminopyrimidin-4(3H)-one+5'-monophosphate+deformylase}}

{{Carbon-nitrogen non-peptide hydrolases}}
{{Enzymes}}

[[Category:EC 3.5.1]]

{{Sourceattribution|2-amino-5-formylamino-6-ribosylaminopyrimidin-4(3H)-one 5'-monophosphate deformylase}}