View source for Biology:2-dehydro-3-deoxy-6-phosphogalactonate aldolase

{{Short description|Class of enzymes}}
{{infobox enzyme
| Name       = 2-dehydro-3-deoxy-6-phosphogalactonate aldolase
| EC_number  = 4.1.2.21
| CAS_number = 9030-99-3
| GO_code    = 0008674
| image      =
| width      = 
| caption    =  
}}
The [[Biology:Enzyme|enzyme]] '''2-dehydro-3-deoxy-6-phosphogalactonate aldolase''' ({{EnzExplorer|4.1.2.21}}) [[Chemistry:Catalysis|catalyzes]] the [[Chemistry:Chemical reaction|chemical reaction]]

:2-dehydro-3-deoxy-<small>D</small>-galactonate 6-phosphate <math>\rightleftharpoons</math> pyruvate + <small>D</small>-glyceraldehyde 3-phosphate

This enzyme belongs to the family of [[Biology:Lyase|lyase]]s, specifically the aldehyde-lyases, which cleave carbon-carbon bonds.  The [[Biology:List of enzymes|systematic name]] of this enzyme class is '''2-dehydro-3-deoxy-D-galactonate-6-phosphate D-glyceraldehyde-3-phosphate-lyase (pyruvate-forming)'''. Other names in common use include '''6-phospho-2-keto-3-deoxygalactonate aldolase''', '''phospho-2-keto-3-deoxygalactonate aldolase''', '''2-keto-3-deoxy-6-phosphogalactonic aldolase''', '''phospho-2-keto-3-deoxygalactonic aldolase''', '''2-keto-3-deoxy-6-phosphogalactonic acid aldolase''', '''(KDPGal)aldolase''', '''2-dehydro-3-deoxy-D-galactonate-6-phosphate''', and '''D-glyceraldehyde-3-phosphate-lyase'''.  This enzyme participates in galactose metabolism.

==Structural studies==

As of late 2007, two [[Biology:Tertiary structure|structures]] have been solved for this class of enzymes, with [[Biology:Protein Data Bank|PDB]] accession codes {{PDB link|2V81}} and {{PDB link|2V82}}.

== References ==
{{reflist|1}}
* {{cite book | vauthors = Shuster CW | date = 1966 | title=Carbohydrate Metabolism| chapter = 2-Keto-3-deoxy-6-phosphogalactonic acid aldolase | volume = 9 | pages = 524&ndash;528 | doi = 10.1016/0076-6879(66)09104-3 | series = Methods in Enzymology | isbn = 978-0-12-181809-8 }}

{{Carbon-carbon lyases}}
{{Enzymes}}

[[Category:EC 4.1.2]]
[[Category:Enzymes of known structure]]



{{Sourceattribution|2-dehydro-3-deoxy-6-phosphogalactonate aldolase}}