View source for Biology:21S rRNA (uridine2791-2'-O)-methyltransferase

{{Short description|Class of enzymes}}
{{Infobox enzyme
| Name       = 21S rRNA (uridine2791-2'-O)-methyltransferase
| EC_number  = 2.1.1.168
| CAS_number =
| GO_code    = 
| image      = 
| width      = 
| caption    =  
}}
'''21S rRNA (uridine<sup>2791</sup>-2'-O)-methyltransferase''' ({{EC number|2.1.1.168}}, ''MRM2 (gene)'', ''mitochondrial 21S rRNA methyltransferase'', ''mitochondrial rRNA MTase 2'') is an [[Biology:Enzyme|enzyme]] with [[Biology:List of enzymes|systematic name]] ''S-adenosyl-L-methionine:21S rRNA (uridine<sup>2791</sup>-2'-O-)-methyltransferase''.<ref>{{cite journal | vauthors = Pintard L, Bujnicki JM, Lapeyre B, Bonnerot C | title = MRM2 encodes a novel yeast mitochondrial 21S rRNA methyltransferase | journal = The EMBO Journal | volume = 21 | issue = 5 | pages = 1139–47 | date = March 2002 | pmid = 11867542 | pmc = 125888 | doi = 10.1093/emboj/21.5.1139 }}</ref> This enzyme [[Chemistry:Catalysis|catalyses]] the following [[Chemistry:Chemical reaction|chemical reaction]]

: S-adenosyl-L-methionine + [[Chemistry:Uridine|uridine]]<sup>279</sup>1 in 21S rRNA <math>\rightleftharpoons</math> S-adenosyl-L-homocysteine + 2'-O-methyluridine<sup>2791</sup> in 21S rRNA

The enzyme catalyses the [[Biology:Methylation|methylation]] of [[Chemistry:Uridine|uridine]]<sup>2791</sup> of [[Biology:Mitochondria|mitochondria]]l [[Biology:Ribosomal RNA|21S rRNA]].

== References ==
{{reflist}}

== External links ==
* {{MeshName|21S+rRNA+(uridine2791-2'-O)-methyltransferase}}

{{One carbon transferases}}
{{Enzymes}}

[[Category:EC 2.1.1]]

{{Sourceattribution|21S rRNA (uridine2791-2'-O)-methyltransferase}}