View source for Biology:Cis-1,2-dihydro-1,2-dihydroxynaphthalene dehydrogenase

{{Short description|Class of enzymes}}
{{infobox enzyme
| Name       = cis-1,2-dihydro-1,2-dihydroxynaphthalene dehydrogenase
| EC_number  = 1.3.1.29
| CAS_number = 53986-49-5
| GO_code    = 0018505
| image      =
| width      = 
| caption    =  
}}
In [[Biology:Enzymology|enzymology]], a '''cis-1,2-dihydro-1,2-dihydroxynaphthalene dehydrogenase''' ({{EC number|1.3.1.29}}) is an [[Biology:Enzyme|enzyme]] that [[Chemistry:Catalysis|catalyzes]] the [[Chemistry:Chemical reaction|chemical reaction]]

:cis-1,2-dihydronaphthalene-1,2-diol + NAD<sup>+</sup> <math>\rightleftharpoons</math> naphthalene-1,2-diol + NADH + H<sup>+</sup>

Thus, the two [[Biology:Substrate (biochemistry)|substrates]] of this enzyme are cis-1,2-dihydronaphthalene-1,2-diol and [[Chemistry:Nicotinamide adenine dinucleotide|NAD<sup>+</sup>]], whereas its 3 [[Chemistry:Product|products]] are naphthalene-1,2-diol, [[Chemistry:Nicotinamide adenine dinucleotide|NADH]], and [[Physics:Hydrogen ion|H<sup>+</sup>]].

This enzyme belongs to the family of [[Biology:Oxidoreductase|oxidoreductase]]s, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor.  The [[Biology:List of enzymes|systematic name]] of this enzyme class is '''cis-1,2-dihydronaphthalene-1,2-diol:NAD+ 1,2-oxidoreductase'''. Other names in common use include '''(+)-cis-naphthalene dihydrodiol dehydrogenase''', '''naphthalene dihydrodiol dehydrogenase''', and '''cis-dihydrodiol naphthalene dehydrogenase'''.  This enzyme participates in 1- and 2-methylnaphthalene degradation and naphthalene and anthracene degradation.

==References==
{{reflist|1}}
* {{cite journal |vauthors=Patel TR, Gibson DT | date = 1974 | title = Purification and properties of (plus)-cis-naphthalene dihydrodiol dehydrogenase of Pseudomonas putida | journal = J. Bacteriol.  | volume = 119 | pages = 879–88  | pmid = 4369091 | issue = 3 | pmc = 245694 }}

{{CH-CH oxidoreductases}}
{{Enzymes}}

[[Category:EC 1.3.1]]
[[Category:NADH-dependent enzymes]]
[[Category:Enzymes of unknown structure]]



{{Sourceattribution|Cis-1,2-dihydro-1,2-dihydroxynaphthalene dehydrogenase}}