View source for Biology:Near-equilibrium enzymatic flux transfer networks

{{Proposed deletion/dated
  |concern = I think this is a term that didn't really catch on. When I search Pubmed or GScholar the only hit I see is the 2003 review cited here. I don't think this topic meets WP:GNG at this time.
  |timestamp = 20200718190516
  |nom = Ajpolino
  |help = off
}}

'''Near-equilibrium enzymatic flux transfer networks''' are intra-cellular mechanisms for moving [[Chemistry:Adenosine triphosphate|ATP]] and a wide range of other [[Biology:Metabolite|metabolite]]s around the [[Biology:Cell|cell]] from where they are produced to where they are needed, at a rate faster than simple [[Physics:Diffusion|diffusion]] through the cell's [[Biology:Cytoplasm|cytoplasm]]. They can act as a buffer system, as there are linear arrays of pathways with several intermediates in the chain, making the supply of metabolites more reliable. A set of parallel shuttles is also less sensitive to disruption than a single shuttle would be. This allows for automatic coupling between supply and demand, and they can almost instantly supply of a ligand to parts of cells that require it. Hence the concentrations of enzymes in the cell is very large (as opposed to a high concentration of metabolites or solutes) which helps [[Physics:Osmosis|osmotic]] [[Homeostasis|homeostasis]], and means transport of metabolites is not dependent on wastefully large [[Physics:Concentration gradient|concentration gradient]]s. This means that they are less costly in terms of energy used.<ref>{{cite journal|url=http://jeb.biologists.org/cgi/content/full/206/12/2039|title= Review: Phosphotransfer networks and cellular energetics|first1= Petras P. |last1=Dzeja|first2=Andre|last2=Terzic|journal=The Journal of Experimental Biology |date=2003|volume=206|pages=2039–2047}}</ref>

==References==
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[[Category:Cell biology]]



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