View source for Chemistry:Guacetisal

{{Short description|Chemical compound}}
{{Verification|date=November 2023}}{{Drugbox
| drug_name =
| IUPAC_name        = 2-Methoxyphenyl 2-acetoxybenzoate
| image             = Guacetisal.svg
| alt               =
| caption           =

<!-- Clinical data -->
| tradename         = Broncaspin; Balsacetil; Guaiaspir; Prontomucil
| Drugs.com         =
| MedlinePlus       =
| pregnancy_AU      = <!-- A / B1 / B2 / B3 / C / D / X -->
| pregnancy_US      = <!-- A / B            / C / D / X -->
| pregnancy_category=
| legal_AU = <!-- S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled-->
| legal_CA = <!-- OTC, Rx-only, Schedule I, II, III, IV, V, VI, VII, VIII -->
| legal_UK = <!-- GSL, P, POM, CD, CD Lic, CD POM, CD No Reg POM, CD (Benz) POM, CD (Anab) POM or CD Inv POM -->
| legal_US = <!-- OTC / Rx-only / Schedule I, II, III, IV, V -->
| legal_status      =
| routes_of_administration =

<!-- Pharmacokinetic data -->
| bioavailability   =
| protein_bound     =
| metabolism        =
| elimination_half-life =
| excretion         =

<!-- Identifiers -->
| CAS_number        = 55482-89-8
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = T6EKB9V2O2
| ATCvet            =
| ATC_prefix        = N02
| ATC_suffix        = BA14
| PubChem           = 68749
| DrugBank          =
| ChEMBL =  2105097
| ChemSpiderID      = 61994
| synonyms          = Aspirin guaiacol ester; ''O''-Methoxyphenyl salicylate acetate

<!-- Chemical data -->
| C=16 | H=14 | O=5
| smiles            = O=C(Oc1ccccc1C(=O)Oc2ccccc2OC)C
| StdInChI          = 1S/C16H14O5/c1-11(17)20-13-8-4-3-7-12(13)16(18)21-15-10-6-5-9-14(15)19-2/h3-10H,1-2H3
| StdInChIKey       = HSJFYRYGGKLQBT-UHFFFAOYSA-N
| melting_point     = 72
| melting_high      = 74.5
}}

'''Guacetisal''' is a drug that has been used to treat [[Medicine:Inflammation|inflammatory]] respiratory diseases.<ref>{{cite journal | vauthors = Vizioli A, Zamperini D, Ursaia G | title = [Clinical trial of guacetisal in aged subjects with inflammatory diseases of the respiratory tract] | journal = La Clinica Terapeutica | volume = 103 | issue = 5 | pages = 527–33 | date = December 1982 | pmid = 6761043 }}</ref>  Chemically, it is an [[Chemistry:Ester|ester]] resulting from the combination of [[Chemistry:Aspirin|aspirin]] and [[Chemistry:Guaiacol|guaiacol]].{{cn|date=February 2022}}

== References ==
{{Reflist}}

{{Anti-inflammatory products}}
{{Prostanoidergics}}

[[Category:Salicylate esters]]
[[Category:Acetylsalicylic acids]]
[[Category:Catechol ethers]]


{{Sourceattribution|Guacetisal}}