View source for Medicine:DTaP-Hib vaccine

{{Short description|Combination vaccine}}
{{Drugbox
| Verifiedfields =
| Watchedfields =
| verifiedrevid =
| image =
| drug_name  =
| type       = combo
| component1 = DTaP vaccine
| class1     = [[Biology:Vaccine|Vaccine]]
| component2 = Hib vaccine
| class2     = [[Biology:Vaccine|Vaccine]]
<!-- Clinical data -->
| pronounce         =
| tradename =  TriHIBit, ActHIB with Tripedia
| Drugs.com =
| MedlinePlus       =
| pregnancy_AU      = <!-- A/B1/B2/B3/C/D/X -->
| pregnancy_US      = C
| pregnancy_category=
| legal_AU          = <!-- S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled-->
| legal_AU_comment =
| legal_BR =  <!-- OTC, A1, A2, A3, B1, B2, C1, C2, C3, C4, C5, D1, D2, E, F-->
| legal_BR_comment =
| legal_CA = <!-- OTC, Rx-only, Schedule I, II, III, IV, V, VI, VII, VIII -->
| legal_UK = <!-- GSL, P, POM, CD, CD Lic, CD POM, CD No Reg POM, CD (Benz) POM, CD (Anab) POM or CD Inv POM -->
| legal_US = <!-- OTC / Rx-only / Schedule I, II, III, IV, V -->
| legal_UN = <!-- N I, II, III, IV / P I, II, III, IV-->
| legal_NZ = <!--Class A, B, C -->
| legal_status      =
| routes_of_administration = Intramuscular injection
<!-- Identifiers -->
| CAS_number        = 1670254-07-5
| ATCvet            =
| ATC_prefix        = J07
| ATC_suffix        = AG52
| PubChem           =
| DrugBank          =
}}

'''DTaP-Hib vaccine''' is a combination vaccine whose generic name is diphtheria and tetanus toxoids and acellular pertussis adsorbed with Haemophilus B conjugate vaccine, sometimes abbreviated to [[Medicine:DPT vaccine|DTaP]]-[[Medicine:Hib vaccine|Hib]].<ref>{{cite web|url=https://www.drugs.com/disease-interactions/diphtheria-toxoid-haemophilus-b-conjugate-prp-t-vaccine-pertussis-acellular-tetanus-toxoid,trihibit.html|title=Trihibit (diphtheria toxoid / haemophilus b conjugate (prp-t) vaccine / pertussis, acellular / tetanus toxoid) Disease Interactions|access-date=15 July 2018|publisher=Drugs.com}}</ref> It protects against the infectious diseases [[Medicine:Diphtheria|diphtheria]], [[Medicine:Tetanus|tetanus]], pertussis, and ''Haemophilus influenzae'' type B.{{cn|date=June 2022}}

A branded formulation was marketed in the US as TriHIBit by [[Company:Sanofi Pasteur|Sanofi Pasteur]], and administered by using the Sanofi [[Medicine:DPT vaccine|DTaP vaccine]] Tripedia to reconstitute the Sanofi [[Medicine:Hib vaccine|Hib vaccine]] ActHIB.<ref>{{cite web|url=https://www.cdc.gov/mmwr/preview/mmwrhtml/00044501.htm|title=Notice to Readers FDA Approval of a Haemophilus b Conjugate Vaccine Combined by Reconstitution with an Acellular Pertussis Vaccine|publisher=Centers for Disease Control and Prevention|access-date=15 July 2018|work=Morbidity and Mortality Weekly Report|volume=45|issue=45|pages=993–995|date=15 November 1996}}</ref><ref>{{cite web|archive-url=https://wayback.archive-it.org/7993/20170112211659/http:/www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM101580.pdf|archive-date=12 January 2017|title=Tripedia package insert|url=https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM101580.pdf|url-status=dead|publisher=US Food and Drug Administration|access-date=15 July 2018}}</ref><ref>{{cite web|url=https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM109841.pdf|title=ActHIB package insert|publisher=US Food and Drug Administration|access-date=15 July 2018}}</ref> TriHIBit and Tripedia were discontinued in 2011.<ref>{{cite web|url=https://www.cdc.gov/vaccines/pubs/pinkbook/downloads/appendices/B/discontinued_vaccines.pdf|title=Selected Discontinued U.S. Vaccines|publisher=Centers for Disease Control and Prevention|access-date=15 July 2018}}</ref> The current Sanofi DTaP formulation is Daptacel.{{cn|date=February 2023}}

==References==
{{Reflist}}

{{Vaccines}}

[[Category:Diphtheria]]
[[Category:Haemophilus]]
[[Category:Tetanus]]
[[Category:Vaccines]]



{{Sourceattribution|DTaP-Hib vaccine}}