View source for Medicine:Inflammatory fibroid polyp

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| name            = Inflammatory fibroid polyp
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| image           = Inflammatory fibroid polyp - low mag.jpg
| caption         = [[Micrograph]] of an inflammatory fibroid polyp. H&E stain.
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'''Inflammatory fibroid polyp''' ('''IFP''') is a benign abnormal growth of tissue projecting into the [[Biology:Lumen (anatomy)|lumen]] of the [[Biology:Gastrointestinal tract|gastrointestinal tract]].

==Pathology==
IFPs consist of spindle cells that are concentrically arranged around blood vessels and have inflammation, especially eosinophils.<ref name=pmid20393746>{{Cite journal  | last1 = Daum | first1 = O. | last2 = Hatlova | first2 = J. | last3 = Mandys | first3 = V. | last4 = Grossmann | first4 = P. | last5 = Mukensnabl | first5 = P. | last6 = Benes | first6 = Z. | last7 = Michal | first7 = M. | title = Comparison of morphological, immunohistochemical, and molecular genetic features of inflammatory fibroid polyps (Vanek's tumors). | journal = Virchows Arch | volume = 456 | issue = 5 | pages = 491–7 |date=May 2010 | doi = 10.1007/s00428-010-0914-8 | PMID = 20393746 }}</ref>
They may have [[Medicine:Leiomyoma|leiomyoma]]/schwannoma-like areas with nuclear palisading.

They typically stain with [[Biology:CD34|CD34]]<ref name=pmid20393746/> and vimentin,<ref>{{Cite journal  | last1 = Kolodziejczyk | first1 = P. | last2 = Yao | first2 = T. | last3 = Tsuneyoshi | first3 = M. | title = Inflammatory fibroid polyp of the stomach. A special reference to an immunohistochemical profile of 42 cases. | journal = Am J Surg Pathol | volume = 17 | issue = 11 | pages = 1159–68 |date=Nov 1993 | doi =  10.1097/00000478-199311000-00009| PMID = 8214261 }}</ref> and, generally, do not stain with [[Biology:CD117|CD117]] and S100.

The endoscopic [[Medicine:Differential diagnosis|differential diagnosis]] includes other benign, pre-malignant and malignant gastrointestinal [[Medicine:Polyp|polyps]].

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Image:Inflammatory_fibroid_polyp_-_high_mag.jpg | High mag.
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=== Morphological differential diagnosis ===
*[[Medicine:Inflammatory myofibroblastic tumour|Inflammatory myofibroblastic tumour]] (IMT)

== See also ==


* Inflammatory pseudotumor

==References==
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[[Category:Digestive system]]

{{Sourceattribution|Inflammatory fibroid polyp|1}}