View source for Template:Cholesterol and steroid metabolism enzymes

{{Navbox
| name       = Cholesterol and steroid metabolism enzymes
| title      = [[Biology:Metabolism|Metabolism]]: [[Biology:Lipid metabolism|lipid metabolism]] – [[Chemistry:Ketone|ketone]]s/[[Chemistry:Cholesterol|cholesterol]] synthesis [[Biology:Enzymes|enzymes]]/[[steroid metabolism]]
| listclass  = hlist
| titlestyle = background:#e7dcc3
| groupstyle = background-color: AntiqueWhite

| group1     = [[Biology:Mevalonate pathway|Mevalonate pathway]]
| list1      =
  {{Navbox|subgroup
  | groupstyle = background-color: AntiqueWhite

  | group1 = To [[Chemistry:HMG-CoA|HMG-CoA]]
  | list1  = 
* [[Biology:Thiolase|Acetyl-Coenzyme A acetyltransferase]]
* [[HMG-CoA synthase]]  (regulated step)

  | group2 = [[Biology:Ketogenesis|Ketogenesis]]
  | list2  = 
* [[Biology:3-hydroxy-3-methylglutaryl-CoA lyase|HMG-CoA lyase]]
* [[3-hydroxybutyrate dehydrogenase]]
* [[Thiophorase]]

  | group3 = To [[Chemistry:Mevalonic acid|Mevalonic acid]]
  | list3  = 
* [[Biology:HMG-CoA reductase|HMG-CoA reductase]]

  | group4 = To [[Chemistry:Dimethylallyl pyrophosphate|DMAPP]]
  | list4  = 
* [[Biology:Mevalonate kinase|Mevalonate kinase]]
* [[Biology:Phosphomevalonate kinase|Phosphomevalonate kinase]]
* [[Pyrophosphomevalonate decarboxylase]]
* [[Biology:Isopentenyl-diphosphate delta isomerase|Isopentenyl-diphosphate delta isomerase]]

  | group5 = Geranyl-
  | list5  = 
* [[Biology:Dimethylallyltranstransferase|Dimethylallyltranstransferase]]
* [[Chemistry:Geranyl pyrophosphate|Geranyl pyrophosphate]]
  }}

| group5     = To [[Chemistry:Cholesterol|cholesterol]]
| list5      =
  {{Navbox|subgroup
  | groupstyle = background-color: AntiqueWhite

  | group1 = To [[Chemistry:Lanosterol|lanosterol]]
  | list1  = 
* [[Biology:Farnesyl-diphosphate farnesyltransferase|Farnesyl-diphosphate farnesyltransferase]]
* [[Biology:Squalene monooxygenase|Squalene monooxygenase]]
* [[Biology:Lanosterol synthase|Lanosterol synthase]]

  | group2 = [[Chemistry:7-Dehydrocholesterol|7-Dehydrocholesterol]] path
  | list2  = 
* [[Lanosterol 14α-demethylase]]
* [[Sterol-C5-desaturase-like]]
* [[Biology:7-Dehydrocholesterol reductase|7-Dehydrocholesterol reductase]]

  | group3 = [[Chemistry:Desmosterol|Desmosterol]] path
  | list3  = 
* [[Biology:24-Dehydrocholesterol reductase|24-Dehydrocholesterol reductase]]
  }}

| group6 = To [[Chemistry:Bile acid|Bile acid]]s  
| list6  = 
* [[Cholesterol 7α-hydroxylase]]
* [[Biology:CYP27A1|Sterol 27-hydroxylase]]

| group7     = [[Steroidogenesis]]
| list7      =
  {{Navbox|subgroup
  | groupstyle = background-color: AntiqueWhite

  | group1 = To [[Chemistry:Pregnenolone|pregnenolone]]
  | list1  = 
* [[Biology:Cholesterol side-chain cleavage enzyme|Cholesterol side-chain cleavage]]

  | group2 = To [[Biology:Corticosteroid|corticosteroid]]s
  | list2  = 
* ''[[Chemistry:Aldosterone|aldosterone]]:'' [[Biology:Aldosterone synthase|18-Hydroxylase]]

* ''[[Chemistry:Cortisol|cortisol]]/[[Chemistry:Cortisone|cortisone]]:'' [[Biology:CYP17A1|17α-Hydroxylase]]
* [[Biology:11β-Hydroxysteroid dehydrogenase|11β-{{abbr|HSD|Hydroxysteroid dehydrogenase}}]]
** [[Biology:11β-Hydroxysteroid dehydrogenase type 1|1]]
** [[11β-Hydroxysteroid dehydrogenase type 2|2]]

* ''both:'' [[Biology:3β-Hydroxysteroid dehydrogenase|3β-{{abbr|HSD|Hydroxysteroid dehydrogenase}}]]
** [[HSD3B1|1]]
** [[HSD3B2|2]]
* [[Biology:21-Hydroxylase|21-Hydroxylase]]
* [[11β-Hydroxylase]]

  | group3     = To [[Biology:Sex hormone|sex hormone]]s
  | list3      =
    {{Navbox|subgroup
    | groupstyle = background-color: AntiqueWhite

    | group1 = To [[Biology:Androgen|androgen]]s
    | list1  = 
* [[Biology:CYP17A1|17α-Hydroxylase]]
* [[Biology:CYP17A1|17,20-Lyase]]
* [[Biology:3β-Hydroxysteroid dehydrogenase|3β-{{abbr|HSD|Hydroxysteroid dehydrogenase}}]]
* [[Biology:17β-Hydroxysteroid dehydrogenase|17β-{{abbr|HSD|Hydroxysteroid dehydrogenase}}]]
* [[5-alpha reductase|5α-Reductase]]
** [[SRD5A1|1]]
** [[SRD5A2|2]]

    | group2 = To [[Biology:Estrogen|estrogen]]s
    | list2  = 
* [[Biology:Aromatase|Aromatase]] 
* [[Biology:17β-Hydroxysteroid dehydrogenase|17β-{{abbr|HSD|Hydroxysteroid dehydrogenase}}]]

  }}

| group5 = Other/ungrouped
| list5  = 
* [[Steroid metabolism]]: ''[[Biology:Sulfatase|sulfatase]]''
** [[Biology:Steroid sulfatase|Steroid sulfatase]]
* ''[[Biology:Sulfotransferase|sulfotransferase]]''
** [[SULT1A1]]
** [[SULT2A1]]

* [[Biology:Steroidogenic acute regulatory protein|Steroidogenic acute regulatory protein]]
* [[Chemistry:Cholesterol total synthesis|Cholesterol total synthesis]]
* [[Biology:Reverse cholesterol transport|Reverse cholesterol transport]]
}}

}}<noinclude>
[[Category:Lipid metabolic pathway templates]]
</noinclude>