Biology:PhTx-1: Difference between revisions
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Short description: Toxic fraction
PhTx-1 is a toxic fraction isolated from the venom of the Brazilian wandering spider Phoneutria nigriventer.
Composition and Target
PhTx-1 has as its main toxin PnTx-1, with a molecular mass of 8,594.6 Da, composed of 77 aminoacid residues, 14 of which are cysteines.[1] PnTx-1, also known as Tx1, exerts an inhibitory effect on neuronal sodium channels (Nav1.2).[2] This component is considered highly pathogenic for primates.
References
- ↑ Resende, Rodrigo R. (2015-01-01) (in pt-PT). Biotecnologia aplicada à saúde - vol. 1: fundamentos e aplicações. Editora Blucher. ISBN 978-85-212-0897-6. https://books.google.com/books?id=OQC5DwAAQBAJ&q=phtx-1+nigriventer+a%C3%A7%C3%A3o&pg=PA546.
- ↑ Weiss, Marcelo Barros; Paiva, Jorge Wilson Souza (2018-10-10) (in pt-BR). Acidentes com Animais Peçonhentos. Thieme Revinter Publicações LTDA. ISBN 978-85-5465-084-1. https://books.google.com/books?id=NzlyDwAAQBAJ&q=PhTx-2+fra%C3%A7%C3%A3o&pg=PT161.
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