EDEN cohort study
The "étude des déterminants pré et postnatals du développement de la santé de l'enfant" (study of pre and postnatal determinants of the child's health and development), more commonly known as the EDEN cohort study, is a French epidemiological mother-child cohort study conducted by Inserm.[1] The main study aim is to improve the understanding of the role of early life factors that influence the development of children. This study falls in the scientific paradigm of the developmental origins of health and development (DOHaD), also known as the theory of Barker.
The main health outcomes investigated in the cohort include child growth and adiposity, allergies, infections, and cognitive development. Early life factors of interest include maternal diet, nutritional and metabolic status during pregnancy, mental health, other lifestyle factors, environmental factors, social determinants, and genetic and epigenetic markers.
From 2003 to 2006, the study recruited 2002 pregnant women in the maternity unit of Nancy and Poitiers hospitals. After delivery, 1907 infants were enrolled in the cohort and followed up with regular clinical and psychological examinations and questionnaires sent to the parents. The study is still active.
More than 15 research teams contribute to the EDEN study and more than 120 peer-reviewed articles have been published so far.
References
- ↑ Heude, Barbara; Forhan, Anne; Slama, Rémy; Douhaud, Lorraine; Bedel, Sophie; Saurel-Cubizolles, Marie-Josèphe; Hankard, Régis; Thiebaugeorges, Olivier et al. (2016-04-01). "Cohort Profile: The EDEN mother-child cohort on the prenatal and early postnatal determinants of child health and development". International Journal of Epidemiology 45 (2): 353–363. doi:10.1093/ije/dyv151. ISSN 0300-5771. PMID 26283636.
External links
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