Biology:Cytoplasm-to-vacuole targeting
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Short description: Autophagy-related pathway in yeast
Cytoplasm-to-vacuole targeting (Cvt) is an autophagy-related pathway in yeast. Under vegetative conditions it delivers hydrolases, such as aminopeptidase 1 (Ape1), to the vacuole.[1][2] This makes the cvt pathway the only known biosynthetic pathway to utilize the machinery of autophagy for operation.[1]
Nomenclature
The abbreviation Cvt comes from the emphasis Cytoplasm vacuole targeting, not from Cytoplasm-to-vacuole targeting.
References
- ↑ 1.0 1.1 "The Cvt pathway as a model for selective autophagy". FEBS Letters 584 (7): 1359–66. 2010. doi:10.1016/j.febslet.2010.02.013. PMID 20146925. PMC 2843786. https://deepblue.lib.umich.edu/bitstream/2027.42/116339/1/feb2s0014579310001079.pdf.
- ↑ Klionsky, Daniel J. (2005-01-01). "The molecular machinery of autophagy: unanswered questions" (in en). J Cell Sci 118 (1): 7–18. doi:10.1242/jcs.01620. ISSN 0021-9533. PMID 15615779.
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