Chemistry:Phorbol 12,13-dibutyrate
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Revision as of 07:31, 20 September 2021 by imported>John Stpola (fixing)
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Names | |
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Preferred IUPAC name
(1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-4a,7b-Dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-1,1a,1b,4,4a,5,7a,7b,8,9-decahydro-9aH-cyclopropa[3,4]benzo[1,2-e]azulene-9,9a-diyl dibutanoate | |
Other names
Phorbol dibutyrate; Phorbol 12,13-dibutanoate
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Identifiers | |
3D model (JSmol)
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Abbreviations | PDBu |
ChEBI | |
ChemSpider | |
KEGG | |
PubChem CID
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UNII | |
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Properties | |
C28H40O8 | |
Molar mass | 504.620 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
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Infobox references | |
Tracking categories (test):
Phorbol 12,13-dibutyrate (PDBu) is a phorbol ester which is one of the constituents of croton oil. As an activator of protein kinase C, it is a weak tumor promoter compared to 12-O-tetradecanoylphorbol-13-acetate.[1]
PDBu is widely used as a chemical reagent because of its solubility in water and other organic solvents.
References
- ↑ "Phorbol ester receptors and the in vitro effects of tumor promoters". Annals of the New York Academy of Sciences 407 (1): 303–315. 1983. doi:10.1111/j.1749-6632.1983.tb47836.x. PMID 6309054. Bibcode: 1983NYASA.407..303B.
![]() | Original source: https://en.wikipedia.org/wiki/Phorbol 12,13-dibutyrate.
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