Medicine:Clostridial vaccine

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A clostridial vaccine is a vaccine for sheep and cattle that protects against diseases caused by toxins produced by an infection with one or more Clostridium bacteria.[1] Clostridial vaccines are often administered to pregnant ewes a few weeks before they are due to give birth, in order to give passive immunity to their lambs.[1] Clostridial bacteria multiply rapidly in infected sheep, and produce large amounts of toxin which can cause the sheep to die within hours.[2]

Clostridial vaccines can contain anti-toxins to one or more endotoxins produced by the following bacteria:[1]

Clostridial vaccines which protect sheep against multiple clostridial diseases have been available since the 1950s.[3]

References

  1. 1.0 1.1 1.2 Duncanson, Graham R. (2012). "Vaccines for sheep. Clostridial diseases". Veterinary Treatment of Sheep and Goats. CABI. p. 97. ISBN 9781780640051. https://books.google.com/books?id=ynUPNHXayHQC&pg=PA97. 
  2. Scott, Phillip R. (2006). "Clostridial diseases". Sheep Medicine. CRC Press. p. 125. ISBN 9781840765366. https://books.google.com/books?id=whhp7rIQru0C&pg=PA125. 
  3. Sargison, Neil (2009). Sheep flock health: a planned approach. John Wiley & Sons. p. 263. ISBN 9781444302608. https://books.google.com/books?id=-nS2JylUCCEC&pg=PA263.