Template:Oral potencies of estrogens

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v · d · e Oral potencies of estrogens
Estrogen Type Class ETD
(2–3 weeks)		 EPD
(2–3 weeks)		 MSD
(2–3 weeks)		 MSD
(daily)		 OID
(daily)		 TSD
(daily)
Estradiol (non-micronized) Bioidentical Steroidal 30 mg ≥120–300 mg 120 mg 6 mg ? ?
Estradiol (micronized) Bioidentical Steroidal 6–12 mg 60–80 mg 14–42 mg 1–2 mg ? >8 mg
Estradiol valerate Bioidentical Steroidal 6–12 mg 60–80 mg 14–42 mg 1–2 mg ? >8 mg
Estradiol benzoate Bioidentical Steroidal ? 60–140 mg ? ? ? ?
Estriol Bioidentical Steroidal 20 mga 120–150 mgb 28–126 mg 1–6 mg ? ?
Estriol succinate Bioidentical Steroidal ? 140–150 mgb 28–126 mg 2–6 mg ? ?
Estrone sulfate Bioidentical Steroidal 12 mg 60 mg 42 mg 2 mg ? ?
Conjugated estrogens Natural Steroidal 5–12 mg 60–80 mg 8.4–25 mg 0.625–1.25 mg ? 7.5 mg
Ethinylestradiol Synthetic Steroidal 200 μg 1–2 mg 280 μg 20–40 μg 100 μg 100 μg
Mestranol Synthetic Steroidal 300 μg 1.5–3.0 mg 300–600 μg 25–30 μg ? ?
Quinestrol Synthetic Steroidal 300 μg 2–4 mg 500 μg 25–50 μg ? ?
Methylestradiol Synthetic Steroidal ? 2 mg ? ? ? ?
Diethylstilbestrol Synthetic Nonsteroidal 2.5 mg 20–30 mg 11 mg 0.5–2.0 mg ? 3 mg
Diethylstilbestrol dipropionate Synthetic Nonsteroidal ? 15–30 mg ? ? ? ?
Dienestrol Synthetic Nonsteroidal 5 mg 30–40 mg 42 mg 0.5–4.0 mg ? ?
Dienestrol diacetate Synthetic Nonsteroidal 3–5 mg 30–60 mg ? ? ? ?
Hexestrol Synthetic Nonsteroidal ? 70–110 mg ? ? ? ?
Hexestrol diacetate Synthetic Nonsteroidal ? 45 mg ? ? ? ?
Chlorotrianisene Synthetic Nonsteroidal ? >100 mg ? ? ? ?
Methallenestril Synthetic Nonsteroidal ? 400 mg ? ? ? ?
Footnotes: a = Very variable, often higher. b = In divided doses, 3x/day; irregular and atypical proliferation. Sources: [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16]
Template documentation

See also

References

  1. ↑ "Clinical use of oestrogens and progestogens". Maturitas 12 (3): 199–214. September 1990. doi:10.1016/0378-5122(90)90004-P. PMID 2215269. 
  2. ↑ "Östrogen-therapie in der Praxis. 3: Östrogen-Präparate und -Kombinationspräparate" (in German). Fortschr. Med. 95 (21): 1388–92. June 1977. PMID 559617. 
  3. ↑ Alfred S. Wolf; H.P.G. Schneider (12 March 2013). Östrogene in Diagnostik und Therapie. Springer-Verlag. pp. 78–. ISBN 978-3-642-75101-1. https://books.google.com/books?id=IArLBgAAQBAJ&pg=PA78. 
  4. ↑ Gunther Göretzlehner; Christian Lauritzen; Thomas Römer; Winfried Rossmanith (1 January 2012). Praktische Hormontherapie in der Gynäkologie. Walter de Gruyter. pp. 44–. ISBN 978-3-11-024568-4. https://books.google.com/books?id=TIs2WhfYzZ4C&pg=PA44. 
  5. ↑ Karl Knörr; Fritz K. Beller; Christian Lauritzen (17 April 2013). Lehrbuch der Gynäkologie. Springer-Verlag. pp. 212–213. ISBN 978-3-662-00942-0. https://books.google.com/books?id=ACybBwAAQBAJ&pg=PA212. 
  6. ↑ Horský, Jan; Presl, Jiří (1981). "Hormonal Treatment of Disorders of the Menstrual Cycle". Ovarian Function and its Disorders: Diagnosis and Therapy. Springer Science & Business Media. pp. 309–332. doi:10.1007/978-94-009-8195-9_11. ISBN 978-94-009-8195-9. https://books.google.com/books?id=7IrpCAAAQBAJ&pg=PA145. 
  7. ↑ Willibald Pschyrembel (1968). Praktische Gynäkologie: für Studierende und Ärzte. Walter de Gruyter. pp. 598–599. ISBN 978-3-11-150424-7. https://books.google.com/books?id=vVaTnHDFzZ0C&pg=PA598. 
  8. ↑ "The female climacteric syndrome: significance, problems, treatment". Acta Obstet Gynecol Scand Suppl 51: 47–61. January 1976. doi:10.3109/00016347509156433. PMID 779393. 
  9. ↑ Lauritzen, Ch. (1975). "The Female Climacteric Syndrome: Significance, Problems, Treatment". Acta Obstetricia et Gynecologica Scandinavica 54 (s51): 48–61. doi:10.3109/00016347509156433. ISSN 0001-6349. 
  10. ↑ Kopera, Hans (1991). "Hormone der Gonaden". Hormonelle Therapie für die Frau. pp. 59–124. doi:10.1007/978-3-642-95670-6_6. ISBN 978-3-642-95670-6. 
  11. ↑ "Hormonal Therapy of Prostatic Cancer". Cancer 45 Suppl 7: 1929–1936. April 1980. doi:10.1002/cncr.1980.45.s7.1929. PMID 29603164. 
  12. ↑ "Hormonal Treatment of Transgender Women with Oral Estradiol". Transgend Health 3 (1): 74–81. 2018. doi:10.1089/trgh.2017.0035. PMID 29756046. 
  13. ↑ Rydén, Ake B. V. (1950). "Natural and synthetic oestrogenic substances: their relative effectiveness when administered orally". Acta Endocrinologica 4 (2): 121–139. doi:10.1530/acta.0.0040121. ISSN 0804-4643. 
  14. ↑ "The effectiveness of natural and synthetic oestrogenic substances in women". Acta Endocrinol. 8 (2): 175–91. 1951. doi:10.1530/acta.0.0080175. PMID 14902290. 
  15. ↑ Kottmeier, Hans Ludvig (1947). "Ueber blutungen in der menopause: Speziell der klinischen bedeutung eines endometriums mit zeichen hormonaler beeinflussung: Part I". Acta Obstetricia et Gynecologica Scandinavica 27 (s6): 1–121. doi:10.3109/00016344709154486. ISSN 0001-6349. "There is no doubt that the conversion of the endometrium with injections of both synthetic and native estrogenic hormone preparations succeeds, but the opinion whether native, orally administered preparations can produce a proliferation mucosa changes with different authors. PEDERSEN-BJERGAARD (1939) was able to show that 90% of the folliculin taken up in the blood of the vena portae is inactivated in the liver. Neither KAUFMANN (1933, 1935), RAUSCHER (1939, 1942) nor HERRNBERGER (1941) succeeded in bringing a castration endometrium into proliferation using large doses of orally administered preparations of estrone or estradiol. Other results are reported by NEUSTAEDTER (1939), LAUTERWEIN (1940) and FERIN (1941); they succeeded in converting an atrophic castration endometrium into an unambiguous proliferation mucosa with 120–300 mg oestradiol or with 380 mg oestrone.". 
  16. ↑ N. Rietbrock; A.H. Staib; D. Loew (11 March 2013). Klinische Pharmakologie: Arzneitherapie. Springer-Verlag. pp. 426–. ISBN 978-3-642-57636-2. https://books.google.com/books?id=FkwEBgAAQBAJ&pg=PA426. 
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