Biology:SDCCAG8
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 Generic protein structure example |
Serologically defined colon cancer antigen 8 is a protein that in humans is encoded by the SDCCAG8 gene.[1][2] This protein localizes to the centrioles.[3]
Clinical significance
Mutations in SDCCAG8 have been found to cause nephronophthisis-related ciliopathies.[3]
Interactions
SDCCAG8 has been shown to interact directly with OFD1, a protein that is also associated with nephronophthisis-related ciliopathies.[3]
References
- ↑ "Characterization of human colon cancer antigens recognized by autologous antibodies". Int J Cancer 76 (5): 652–8. Jun 1998. doi:10.1002/(SICI)1097-0215(19980529)76:5<652::AID-IJC7>3.0.CO;2-P. PMID 9610721.
- ↑ "Entrez Gene: SDCCAG8 serologically defined colon cancer antigen 8". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10806.
- ↑ 3.0 3.1 3.2 "Candidate exome capture identifies mutation of SDCCAG8 as the cause of a retinal-renal ciliopathy". Nat. Genet. 42 (10): 840–50. October 2010. doi:10.1038/ng.662. PMID 20835237.
Further reading
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. 2004. doi:10.1101/gr.2596504. PMID 15489334.
- "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.". Nat. Biotechnol. 22 (6): 707–16. 2005. doi:10.1038/nbt971. PMID 15146197.
- "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. 2004. doi:10.1038/ng1285. PMID 14702039.
- "Proteomic characterization of the human centrosome by protein correlation profiling.". Nature 426 (6966): 570–4. 2003. doi:10.1038/nature02166. PMID 14654843. Bibcode: 2003Natur.426..570A.
- "Identification and characterization of the novel centrosome-associated protein CCCAP.". Gene 303: 35–46. 2003. doi:10.1016/S0378-1119(02)01141-1. PMID 12559564.
- "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. 2003. doi:10.1073/pnas.242603899. PMID 12477932.
- "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells.". Genome Res. 10 (10): 1546–60. 2001. doi:10.1101/gr.140200. PMID 11042152.
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