Biology:RTN2
From HandWiki
Short description: Protein-coding gene in the species Homo sapiens
 Generic protein structure example |
Reticulon-2 is a protein that in humans is encoded by the RTN2 gene.[1][2][3]
This gene belongs to the family of reticulon encoding genes. Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. Alternatively spliced transcript variants encoding different isoforms have been identified.[3]
References
- ↑ "Detailed comparative map of human chromosome 19q and related regions of the mouse genome". Genomics 35 (3): 499–508. Dec 1996. doi:10.1006/geno.1996.0390. PMID 8812484. https://zenodo.org/record/1229687.
- ↑ "Molecular cloning of a novel mouse gene with predominant muscle and neural expression". Mamm Genome 9 (4): 274–82. May 1998. doi:10.1007/s003359900748. PMID 9530622.
- ↑ 3.0 3.1 "Entrez Gene: RTN2 reticulon 2". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6253.
Further reading
- Ballif BA; Villén J; Beausoleil SA et al. (2005). "Phosphoproteomic analysis of the developing mouse brain". Mol. Cell. Proteomics 3 (11): 1093–101. doi:10.1074/mcp.M400085-MCP200. PMID 15345747.
- He W; Lu Y; Qahwash I et al. (2004). "Reticulon family members modulate BACE1 activity and amyloid-beta peptide generation". Nat. Med. 10 (9): 959–65. doi:10.1038/nm1088. PMID 15286784.
- Reuter TY; Medhurst AL; Waisfisz Q et al. (2003). "Yeast two-hybrid screens imply involvement of Fanconi anemia proteins in transcription regulation, cell signaling, oxidative metabolism, and cellular transport". Exp. Cell Res. 289 (2): 211–21. doi:10.1016/S0014-4827(03)00261-1. PMID 14499622.
- "A reticular rhapsody: phylogenic evolution and nomenclature of the RTN/Nogo gene family". FASEB J. 17 (10): 1238–47. 2003. doi:10.1096/fj.02-1166hyp. PMID 12832288. http://nbn-resolving.de/urn:nbn:de:bsz:352-opus-39197.
- Strausberg RL; Feingold EA; Grouse LH et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M.
- "Nspl1, a new Z-band-associated protein". J. Muscle Res. Cell. Motil. 20 (7): 661–8. 2000. doi:10.1023/A:1005533013926. PMID 10672514.
- "cDNA cloning, genomic organization, and expression of the human RTN2 gene, a member of a gene family encoding reticulons". Genomics 51 (1): 98–106. 1998. doi:10.1006/geno.1997.5175. PMID 9693037.
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