Biology:FGF22
From HandWiki
Short description: Protein
| fibroblast growth factor 22 | |
|---|---|
| Identifiers | |
| Symbol | FGF22 |
| NCBI gene | 27006 |
| HGNC | 3679 |
| OMIM | 605831 |
| RefSeq | NM_020637 |
| UniProt | Q9HCT0 |
| Other data | |
| Locus | Chr. 19 p13.3 |
Fibroblast growth factor 22 is a protein which in humans is encoded by the FGF22 gene.[1][2]
Function
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The mouse homolog of this gene was found to be preferentially expressed in the inner root sheath of the hair follicle, which suggested a role in hair development.[3]
References
- ↑ "FGF22 and its close relatives are presynaptic organizing molecules in the mammalian brain". Cell 118 (2): 257–70. July 2004. doi:10.1016/j.cell.2004.06.025. PMID 15260994.
- ↑ "Receptor specificity of the fibroblast growth factor family. The complete mammalian FGF family". The Journal of Biological Chemistry 281 (23): 15694–700. June 2006. doi:10.1074/jbc.M601252200. PMID 16597617.
- ↑ "Entrez Gene: Fibroblast growth factor 22". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=27006.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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