Biology:Prophage Hp1 holin family
The Prophage Hp1 Hol (Hp1Hol) Family (TC# 1.E.46) consists of a single putative holin (TC# 1.E.46.1.1) of 69 amino acyl residues in length, exhibiting what appears to be a single transmembrane segment (TMS). It is derived from the Bacillota, Clostridium hathewayi DSM 13479. This protein is functionally uncharacterized and does not appear to be homologous to other holins. It does, however, show 31% identity to a heavy metal transporter from Dethiosulfovibrio peptidovorans.[1][2]
See also
Further reading
- Reddy, Bhaskara L.; Saier, Jr.; Milton, H. (2013). "Topological and phylogenetic analyses of bacterial holin families and superfamilies". Biochimica et Biophysica Acta (BBA) - Biomembranes 1828 (11): 2654–2671. doi:10.1016/j.bbamem.2013.07.004. PMID 23856191.
- Saier, Milton H.; Reddy, Bhaskara L. (2015). "Holins in Bacteria, Eukaryotes, and Archaea: Multifunctional Xenologues with Potential Biotechnological and Biomedical Applications". Journal of Bacteriology 197 (1): 7–17. doi:10.1128/JB.02046-14. PMID 25157079.
- Wang, I. N.; Smith, D. L.; Young, R. (2000). "Holins: the protein clocks of bacteriophage infections". Annual Review of Microbiology 54: 799–825. doi:10.1146/annurev.micro.54.1.799. PMID 11018145.
- Young, R.; Bläsi, U. (1995). "Holins: form and function in bacteriophage lysis". FEMS Microbiology Reviews 17 (1–2): 191–205. doi:10.1111/j.1574-6976.1995.tb00202.x. PMID 7669346.
References
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