Biology:KRT23
From HandWiki
 Generic protein structure example |
Keratin, type I cytoskeletal 23 is a protein that in humans is encoded by the KRT23 gene.[1][2][3]
The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratin and hair keratin. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. The type I cytokeratin genes are clustered in a region of chromosome 17q12-q21.[3]
References
- ↑ "Keratin 23 (K23), a novel acidic keratin, is highly induced by histone deacetylase inhibitors during differentiation of pancreatic cancer cells". Genes Chromosomes Cancer 30 (2): 123–35. Jan 2001. doi:10.1002/1098-2264(2000)9999:9999<::AID-GCC1070>3.0.CO;2-W. PMID 11135429.
- ↑ "New consensus nomenclature for mammalian keratins". J Cell Biol 174 (2): 169–74. Jul 2006. doi:10.1083/jcb.200603161. PMID 16831889.
- ↑ 3.0 3.1 "Entrez Gene: KRT23 keratin 23 (histone deacetylase inducible)". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=25984.
Further reading
- "Single nucleotide polymorphisms associated with aggressive periodontitis and severe chronic periodontitis in Japanese". Biochem. Biophys. Res. Commun. 317 (3): 887–92. 2004. doi:10.1016/j.bbrc.2004.03.126. PMID 15081423.
- "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. 2004. doi:10.1038/ng1285. PMID 14702039.
- "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. 2003. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M.
- "Cytoplasmic intermediate filaments are stably associated with nuclear matrices and potentially modulate their DNA-binding function". DNA Cell Biol. 21 (3): 213–39. 2002. doi:10.1089/10445490252925459. PMID 12015898.
- "Genes for intermediate filament proteins and the draft sequence of the human genome: novel keratin genes and a surprisingly high number of pseudogenes related to keratin genes 8 and 18". J. Cell Sci. 114 (Pt 14): 2569–75. 2002. doi:10.1242/jcs.114.14.2569. PMID 11683385.
- "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene 200 (1–2): 149–56. 1997. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
- "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene 138 (1–2): 171–4. 1994. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
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