Biology:DNA polymerase nu

Short description: Protein-coding gene in the species Homo sapiens

Generic protein structure example

Polymerase (DNA directed) nu is a protein in humans that is encoded by the POLN gene.<ref name="entrez">{{cite web | title = Entrez Gene: Polymerase (DNA directed) nu

Further reading

• "Evidence for the involvement of human DNA polymerase N in the repair of DNA interstrand cross-links". Biochemistry 48 (49): 11817–24. December 2009. doi:10.1021/bi9015346. PMID 19908865. 
• "Rad18 regulates DNA polymerase kappa and is required for recovery from S-phase checkpoint-mediated arrest". Molecular and Cellular Biology 26 (9): 3527–40. May 2006. doi:10.1128/MCB.26.9.3527-3540.2006. PMID 16611994. 
• "DNA polymerase POLN participates in cross-link repair and homologous recombination". Molecular and Cellular Biology 30 (4): 1088–96. February 2010. doi:10.1128/MCB.01124-09. PMID 19995904. 
• "POLN, a nuclear PolA family DNA polymerase homologous to the DNA cross-link sensitivity protein Mus308". The Journal of Biological Chemistry 278 (34): 32014–9. August 2003. doi:10.1074/jbc.M305646200. PMID 12794064. 
• "A unique error signature for human DNA polymerase nu". DNA Repair 6 (2): 213–23. February 2007. doi:10.1016/j.dnarep.2006.09.012. PMID 17118716. 
• "ATR-mediated phosphorylation of DNA polymerase η is needed for efficient recovery from UV damage". The Journal of Cell Biology 192 (2): 219–27. January 2011. doi:10.1083/jcb.201008076. PMID 21242293. 
• "Novel enzymatic function of DNA polymerase nu in translesion DNA synthesis past major groove DNA-peptide and DNA-DNA cross-links". Chemical Research in Toxicology 23 (3): 689–95. March 2010. doi:10.1021/tx900449u. PMID 20102227. 
• "Kinetic analysis of the unique error signature of human DNA polymerase ν". Biochemistry 50 (46): 10126–35. November 2011. doi:10.1021/bi201197p. PMID 22008035. 

External links

• PDBe-KB provides an overview of all the structure information available in the PDB for Human DNA polymerase nu