Biology:STX16
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Short description: Protein-coding gene in the species Homo sapiens
 Generic protein structure example |
Syntaxin-16 is a protein that in humans is encoded by the STX16 gene.[1][2][3][4]
It has been associated with pseudohypoparathyroidism type Ib. Losing this gene causes loss of methylation at GNAS1 exon A/B.[3]
Interactions
STX16 has been shown to interact with VAMP4.[5]
References
- ↑ "Molecular cloning and localization of human syntaxin 16, a member of the syntaxin family of SNARE proteins". Biochemical and Biophysical Research Communications 242 (3): 673–9. Jan 1998. doi:10.1006/bbrc.1997.8029. PMID 9464276.
- ↑ "Syntaxin-16, a putative Golgi t-SNARE". European Journal of Cell Biology 75 (3): 223–31. Mar 1998. doi:10.1016/S0171-9335(98)80116-7. PMID 9587053.
- ↑ 3.0 3.1 "A novel STX16 deletion in autosomal dominant pseudohypoparathyroidism type Ib redefines the boundaries of a cis-acting imprinting control element of GNAS". American Journal of Human Genetics 76 (5): 804–14. May 2005. doi:10.1086/429932. PMID 15800843.
- ↑ "Entrez Gene: STX16 syntaxin 16". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8675.
- ↑ "Early/recycling endosomes-to-TGN transport involves two SNARE complexes and a Rab6 isoform". The Journal of Cell Biology 156 (4): 653–64. Feb 2002. doi:10.1083/jcb.200110081. PMID 11839770.
Further reading
- "Gene expression profiling in human fetal liver and identification of tissue- and developmental-stage-specific genes through compiled expression profiles and efficient cloning of full-length cDNAs". Genome Research 11 (8): 1392–403. Aug 2001. doi:10.1101/gr.175501. PMID 11483580.
- "Early/recycling endosomes-to-TGN transport involves two SNARE complexes and a Rab6 isoform". The Journal of Cell Biology 156 (4): 653–64. Feb 2002. doi:10.1083/jcb.200110081. PMID 11839770.
- "How Tlg2p/syntaxin 16 'snares' Vps45". The EMBO Journal 21 (14): 3620–31. Jul 2002. doi:10.1093/emboj/cdf381. PMID 12110575.
- "Inferring nonneutral evolution from human-chimp-mouse orthologous gene trios". Science 302 (5652): 1960–3. Dec 2003. doi:10.1126/science.1088821. PMID 14671302. Bibcode: 2003Sci...302.1960C.
- "Participation of the syntaxin 5/Ykt6/GS28/GS15 SNARE complex in transport from the early/recycling endosome to the trans-Golgi network". Molecular Biology of the Cell 15 (9): 4011–22. Sep 2004. doi:10.1091/mbc.E03-12-0876. PMID 15215310.
- "Functional proteomics mapping of a human signaling pathway". Genome Research 14 (7): 1324–32. Jul 2004. doi:10.1101/gr.2334104. PMID 15231748.
- "Syntaxin 16 and syntaxin 5 are required for efficient retrograde transport of several exogenous and endogenous cargo proteins". Journal of Cell Science 120 (Pt 8): 1457–68. Apr 2007. doi:10.1242/jcs.03436. PMID 17389686.
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