Biology:NAV1
From HandWiki
Short description: Protein-coding gene in the species Homo sapiens
 Generic protein structure example |
Neuron navigator 1 is a protein that in humans is encoded by the NAV1 gene.[1][2][3]
This gene belongs to the neuron navigator family and is expressed predominantly in the nervous system. The encoded protein contains coiled-coil domains and a conserved AAA domain characteristic for ATPases associated with a variety of cellular activities. This gene is similar to unc-53, a Caenorhabditis elegans gene involved in axon guidance. The exact function of this gene is not known.[3]
References
- ↑ "Neuron navigator: a human gene family with homology to unc-53, a cell guidance gene from Caenorhabditis elegans". Genomics 80 (1): 21–30. Jun 2002. doi:10.1006/geno.2002.6799. PMID 12079279.
- ↑ "Pore membrane and/or filament interacting like protein 1 (POMFIL1) is predominantly expressed in the nervous system and encodes different protein isoforms". Gene 290 (1–2): 73–94. Jun 2002. doi:10.1016/S0378-1119(02)00567-X. PMID 12062803.
- ↑ 3.0 3.1 "Entrez Gene: NAV1 neuron navigator 1". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=89796.
Further reading
- "Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. 2006. doi:10.1101/gr.4039406. PMID 16344560.
- "Sensory deficits in mice hypomorphic for a mammalian homologue of unc-53". Brain Res. Dev. Brain Res. 150 (2): 89–101. 2004. doi:10.1016/j.devbrainres.2004.03.004. PMID 15158073.
- "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. 2004. doi:10.1038/ng1285. PMID 14702039.
- "Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries". DNA Res. 10 (1): 35–48. 2003. doi:10.1093/dnares/10.1.35. PMID 12693553.
- "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. 2003. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M.
- "Protein–Protein Interactions Between Large Proteins: Two-Hybrid Screening Using a Functionally Classified Library Composed of Long cDNAs". Genome Res. 12 (11): 1773–84. 2003. doi:10.1101/gr.406902. PMID 12421765.
- "Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 6 (5): 337–45. 2000. doi:10.1093/dnares/6.5.337. PMID 10574462.
- "Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain". DNA Res. 6 (5): 329–36. 2000. doi:10.1093/dnares/6.5.329. PMID 10574461.
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