Biology:Sperm-associated antigen 5
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Sperm-associated antigen 5 is a protein that in humans is encoded by the SPAG5 gene.[1][2]
This gene encodes a protein associated with the mitotic spindle apparatus. The encoded protein may be involved in the functional and dynamic regulation of mitotic spindles.[2]
References
- ↑ "Cloning and characterization of hMAP126, a new member of mitotic spindle-associated proteins". Biochem Biophys Res Commun 287 (1): 116–21. Sep 2001. doi:10.1006/bbrc.2001.5554. PMID 11549262.
- ↑ 2.0 2.1 "Entrez Gene: SPAG5 sperm associated antigen 5". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10615.
Further reading
- "Interaction of the metalloprotease disintegrins MDC9 and MDC15 with two SH3 domain-containing proteins, endophilin I and SH3PX1". J. Biol. Chem. 274 (44): 31693–9. 1999. doi:10.1074/jbc.274.44.31693. PMID 10531379.
- "Testicular protein Spag5 has similarity to mitotic spindle protein Deepest and binds outer dense fiber protein Odf1". Mol. Reprod. Dev. 59 (4): 410–6. 2001. doi:10.1002/mrd.1047. PMID 11468777.
- "Analysis of mitotic microtubule-associated proteins using mass spectrometry identifies astrin, a spindle-associated protein". Proc. Natl. Acad. Sci. U.S.A. 98 (25): 14434–9. 2002. doi:10.1073/pnas.261371298. PMID 11724960.
- Gruber J; Harborth J; Schnabel J et al. (2003). "The mitotic-spindle-associated protein astrin is essential for progression through mitosis". J. Cell Sci. 115 (Pt 21): 4053–9. doi:10.1242/jcs.00088. PMID 12356910.
- Strausberg RL; Feingold EA; Grouse LH et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M.
- Gerhard DS; Wagner L; Feingold EA et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
- Le XF; Lammayot A; Gold D et al. (2005). "Genes affecting the cell cycle, growth, maintenance, and drug sensitivity are preferentially regulated by anti-HER2 antibody through phosphatidylinositol 3-kinase-AKT signaling". J. Biol. Chem. 280 (3): 2092–104. doi:10.1074/jbc.M403080200. PMID 15504738.
- Yang YC; Hsu YT; Wu CC et al. (2006). "Silencing of astrin induces the p53-dependent apoptosis by suppression of HPV18 E6 expression and sensitizes cells to paclitaxel treatment in HeLa cells". Biochem. Biophys. Res. Commun. 343 (2): 428–34. doi:10.1016/j.bbrc.2006.02.166. PMID 16546135. http://ntur.lib.ntu.edu.tw/bitstream/246246/245936/-1/06.pdf.
- Nousiainen M; Silljé HH; Sauer G et al. (2006). "Phosphoproteome analysis of the human mitotic spindle". Proc. Natl. Acad. Sci. U.S.A. 103 (14): 5391–6. doi:10.1073/pnas.0507066103. PMID 16565220. Bibcode: 2006PNAS..103.5391N.
- Cheng TS; Hsiao YL; Lin CC et al. (2007). "hNinein is required for targeting spindle-associated protein Astrin to the centrosome during the S and G2 phases". Exp. Cell Res. 313 (8): 1710–21. doi:10.1016/j.yexcr.2007.02.023. PMID 17383637. http://ntur.lib.ntu.edu.tw/bitstream/246246/245934/-1/04.pdf.