Biology:UBE2O

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A representation of the 3D structure of the protein myoglobin showing turquoise α-helices.
Generic protein structure example

Ubiquitin-conjugating enzyme E2 O is a protein that in humans is encoded by the UBE2O gene.[1][2][3]

UBE2O functions during terminal erythroid differentiation to eliminate generic cellular components in parallel with abundant synthesis of hemoglobin.[4]

References

  1. "Identification, tissue expression, and chromosomal position of a novel gene encoding human ubiquitin-conjugating enzyme E2-230k". Gene 267 (1): 95–100. Apr 2001. doi:10.1016/S0378-1119(01)00407-3. PMID 11311559. 
  2. "Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res 7 (6): 347–55. Feb 2001. doi:10.1093/dnares/7.6.347. PMID 11214970. 
  3. "Entrez Gene: UBE2O ubiquitin-conjugating enzyme E2O". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=63893. 
  4. "UBE2O remodels the proteome during terminal erythroid differentiation". Science 357 (6350): eaan0218. 2017. doi:10.1126/science.aan0218. PMID 28774900. 

Further reading